tope has recently been proposed as a hypothetical brachytherapy source due to its high specific activity, appropriate half-life (272 days) and medium energy photons (114.17 keV on average). In this study, Task Group No. 43 dosimetric parameters were calculated and reported for a hypothetical 57Co source. Material and methods: A hypothetical 57Co source was simulated in MCNPX, consisting of an a...

background: the effectiveness and safety of brachytherapy treatment is mainly concerned with the calibration of sources and their traceability to internationally accepted standards. secondary standard dosimetry laboratory (ssdl) does not offer calibration of ionization chambers with gamma-ray spectrum of high dose rate source 192ir . this work has been carried out to calibrate the high dose rat...

An experimental brachytherapy model has been developed to study acute and late normal tissue reactions as a tool to examine the effects of clinically relevant multifractionation schedules. Pig skin was used as a model since its morphology, structure, cell kinetics and radiation-induced responses are similar to human skin. Brachytherapy was performed using a microSelectron high dose rate (HDR) a...

background: monte carlo and experimental relative dose determination in a water phantom, due to a high dose rate (hdr) 192ir source is presented for real energy spectrum and monochromatic at 356 kev. materials and methods: the dose distribution has been calculated around the 192ir located in the center of 30 cm ×30 cm ×30 cm water phantom using mcnp4c code by monte carlo method. relative dose v...

In this study, a procedure to test the linear reference air kerma rate of 192Ir wires using a well-type chamber is described. The method is based on a special lead insert with a 1 cm acrylic aperture that provides a differential response of the well chamber. The wire is considered divided into 1 cm parts. Using an external positioning system it is possible to place every part of the wire at the...

BACKGROUND The Washington Radiation for In-Stent Restenosis Trial for long lesions (Long WRIST) was designed to determine the safety and efficacy of vascular brachytherapy for the treatment of diffuse in-stent restenosis. METHODS AND RESULTS A total of 120 patients with diffuse in-stent restenosis in native coronary arteries (lesion length, 36 to 80 mm) were randomized for either radiation wi...

PURPOSE The AccuBoost brachytherapy system applies HDR 192Ir beams peripherally to the breast using collimating applicators. The purpose of this study was to benchmark Monte Carlo simulations of the HDR 192Ir source, to dosimetrically characterize the round applicators using established Monte Carlo simulation and radiation measurement techniques and to gather data for clinical use. METHODS Do...

Beam quality correction, kQQ0(r), for solid-state detectors diamond, LiF, Li2B4O7, Al2O3, and plastic scintillator are calculated as a function of distance, r, along the transverse axis of the 60Co and 192Ir brachytherapy sources using the Monte Carlo- based EGSnrc code system. This study also includes calculation of detector-specific phantom scatter correction, kphan(r), for solid phantoms suc...