نتایج جستجو برای: 1high sensitive c
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background: increased serum high sensitive c-reactive protein (hs-crp) in asthma and its association with disease severity has been investigated in many studies. this study aimed to determine serum hs-crp status in asthma versus healthy controls and to examine its ability in predicting asthma control. methods: serum crp was measured by elisa method using a high sensitive crp kit. severity of as...
Oncolytic viruses (OVs) remodel the tumor microenvironment by switching a “cold” into “hot” with high CD8+ T-cell infiltration. activity plays an essential role in antitumor efficacy of OVs. However, T cells is impaired programmed cell death protein-1/programmed death-ligand 1 (PD-1/PD-L1) interaction. To date, it remains unclear why OVs alone have significant even when PD-L1 expression persist...
Type 1 diabetes is caused by autoreactive T cells that destroy pancreatic beta cells. Animal models suggested that a CD4⁺CD25⁺ population has a regulatory function capable of preventing activation and effector functions of autoreactive T cells. However, the role of CD4⁺CD25high T cells in autoimmunity and their molecular mechanisms remain the subject of investigation. We therefore evaluated T r...
The role of PD-1 expression on CD4 T cells during HIV infection is not well understood. Here, we describe the differential expression of PD-1 in CD127high CD4 T cells within the early/intermediate differentiated (EI) (CD27highCD45RAlow) T cell population among uninfected and HIV-infected subjects, with higher expression associated with decreased viral replication (HIV-1 viral load). A significa...
Critical systems heuristics (Ulrich 1983) is a framework for reflective practice based on practical philosophy and systems thinking. The name stands for three major concerns. First, the aim is to enhance the ‘critical’ (reflective) competence not only of well-trained professionals and decision-makers but also of ordinary people. Second, reflective practice cannot be secured by theoretical means...
Broadcast scheduling algorithms have received a lot of attention recently, since they are important for supporting mobile/ubiquitous computing. However, a comprehensive system's perspective towards the development of high performance broadcast servers is very much lacking. With this paper we attempt to fill this gap. We contribute four novel scheduling algorithms that ensure the proper interpla...
Radiation therapy (RT), a major modality for treating localized tumors, can induce tumor regression outside the radiation field through an abscopal effect that is thought to involve the immune system. Our studies were designed to understand the early immunological effects of RT in the tumor microenvironment using several syngeneic mouse tumor models. We observed that RT induced sterile inflamma...
امروزه گردآورندگان اطلاعات به ویژه سازمان های آماری با دو مسئله متضاد مواجه اند. از یکسو، بنا به وظیفه قانونی و رشد روزافزون تقاضا برای اطلاعات جمعآوری شده، خود را متعهد به انتشار هر چه گسترده تر و باکیفیت تر اطلاعات به شکل داده های آماری می بینند و از سوی دیگر با توجه به نگرانی عمومی نسبت به افشا اطلاعات شخصی و وظیفه قانونی این سازمانها برای مراقبت از اطلاعات خصوصی پاسخگویان، باید این تضمین را...
predictive role of high sensitive c-reactive protein in early onset mortality after ischemic stroke.
background: high sensitive c-reactive protein (hs-crp) is a systemic inflammatory marker that is produced in a large amount by hepatocytes in response to interleukin-1 (il-1), il-6 and tumor necrosis factor after ischemic stroke. methods: measurement of hs-crp in the first 24 hours of onset in 162 patients suffering from ischemic stroke was done. relation of crp with the risk of early mortality...
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