Two newly identified, overlapping (1 bp) glucocorticoid response elements (GREs) at -759 and -773 bp in the promoter of the rat phenylethanolamine N-methyltransferase (PNMT; EC 2.1.1.28) gene are primarily responsible for its glucocorticoid sensitivity, rather than the originally identified -533-bp GRE. A dose-dependent increase in PNMT promoter activity was observed in RS1 cells transfected wi...

Silathiazolidine and metalladithioacetals (M = Si, Ge) have been prepared by the interaction of dialkyldichloro- or bis(diethylamino)dialkylsilanes and -germanes with 3-[N-(2- thioethyl)]amino-propanamide (WR-2529) and [1-thioethyl-2-(1-naphtylmethyl)]-2- imidazoline. The study of these compounds in the field of chemical radioprotection has shown a notable decrease in the toxicity and a rather ...

BACKGROUND The efficacy, acceptability and tolerability of the new oral phosphate binder Lenziaren® (SBR759) were evaluated in a randomized parallel-group design study in 36 healthy cats (n = 6 per group). Five groups were fed once daily with a commercial diet containing 0.2% phosphorus ("standard diet") into which was mixed Lenziaren® at 0.25, 0.5, 1.0 or 2.0 g/day or no treatment (control gro...

Purpose: Anger associated with sports participation may affect inability to acutely process anger, decrease performance and increase the likelihood of risk-taking behavior in collegiate athletes. Therefore, purpose was examine prevalence anger student-athletes across sex, academic status, sport type. Methods: A cross sectional study over a three-year period examined 759 NCAA Division I at one i...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 201 No. 5 759–776 www.jcb.org/cgi/doi/10.1083/jcb.201212100 JCB 759 Correspondence to Roberto Mayor: [email protected]; or Ariel E. Reyes: [email protected] Abbreviations used in this paper: EMT, epithelial to mesenchymal transition; FDX, fluorescein dextran; HIF, hypoxia-inducible transcription factor; MO, morpholino; SS, splice site...

BACKGROUND Same-day diagnosis based on histology is increasingly being offered to patients suspected of breast cancer. We evaluated to which extent same-day diagnosis affected diagnostic accuracy and patients' anxiety levels during the diagnostic phase. PATIENTS AND METHODS All 759 women referred for same-day evaluation of suspicious breast lesions between November 2011-March 2013 were includ...

Faculty of Biological Sciences, Institute for Molecular Biology and Genetics, Chonbuk National University, Jeonju 561-756, Korea. E-mail: [email protected] Research Institute of Advanced Engineering and Technology, Chosun University, Gwangju 501-759, Korea Korea Basic Science Institute, Daejeon 305-333, Korea Department of Resources Engineering, Chosun University, Gwangju 501-759, Korea Rece...