Four novel diimine rhenium(I) carbonyl complexes with the formula [Re(CO)3(L)Br], where L = 2-(4-(9H-carbazol-9-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline (P1), 2-(4-(3,6-di-tert-butyl-9H-carbazol-9-yl)phenyl)-1H-imidazo-[4,5-f][1,10]phenanthroline (P2), 2-(4-(6-(9H-carbazol-9-yl)-9H-3,9-bicarbazol-9-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline (D1), and 2-(4-(3',6'-di-tert-butyl-6-(3...

The carbapenem-hydrolyzing class D β-lactamase OXA-253 was identified in an Acinetobacter baumannii clinical isolate belonging to sequence type 113 (ST113) in Brazil. OXA-253 shares 93.8% amino acid identity with OXA-143. The blaOXA-253 gene is located on a ca. 20-kb plasmid. The genetic environment of the blaOXA-253 gene shares the highest identity with ubiquitous GR2 group plasmids usually ca...

Intrathymic expression of tissue-specific self-Ags can mediate tolerance of self-reactive T cells. However, in this study we define circumstances by which thymic expression of a tissue-specific autoepitope enhances positive selection of disease-causing, self-reactive T cells. An immunodominant gastritogenic epitope, namely the gastric H/K ATPase beta subunit(253-277) (H/Kbeta(253-277)), was att...

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We have obtained long-slit spectra of NGC 253 in the J, H, K, and N bands, broadband images in the J, H, and K s bands, narrowband images centered at the wavelengths of Brγ and H 2 (1,0)S(1), and imaging spectroscopy centered on [Ne II](12.8µm). We have subtracted a composite stellar spectrum from the galaxy spectrum to measure faint emission lines which otherwise would be buried in the complic...

Here, we report the isolation of 31 Acinetobacter baumannii strains producing OXA-253 in a single large Brazilian city. These strains belonged to five different sequence types (STs), including 4 STs not previously associated with blaOXA-253 In all strains, the blaOXA-253 gene was located in a plasmid within a genetic environment similar to what was found previously in Brazil and Italy. The repo...

Purpose: The retinoic acid receptors are expressed from early stages of development in the diverse tissues that make up the vertebrate eye. Their loss has subtle effects on eye development. We adapted sensitive quantitative trait locus (QTL) mapping methods to assess consequences of inactivating alleles of the alpha and beta receptors, Rara and Rarb, on eye and retinal development. Rara is of p...