Pleomorphic variant of lobular carcinoma is a recently described variant of invasive lobular carcinoma. It is reported to be positive for estrogen receptors and progesterone receptors and over express Her2/neu in most cases. We present here a case of invasive variant of pleomorphic lobular carcinoma with coexisting classic and pleomorphic variants of lobular carcinoma in situ along with focal d...

Introduction: Ovarian Cancers account for the greatest number of deaths from malignancies female genital tract and it is fifth leading cause cancer fatalities in women. Surface epithelial tumours are most common, followed by germ cell tumours. Objective: To analyse expression EGFR HER 2neu using Immunohistochemisty different with special reference to surface Epithelial Material Methods: 52 case...

Background: In the present study, we aimed to determine expression of PDL1 and its correlation with TIL in Triple Negative (ER, PR Her 2neu negative) cases breast carcinoma (immune-histochemical study) 
 Methods: Expression PD-L1 was seen on 40 proven triple negative carcinomas (TNBC) correlate it other parameters affecting prognosis disease. All were infiltrating ductal NOS (not otherwise...

INTRODUCTION Breast cancer in young women (<50 years) has been associated with an increased risk of recurrence and decreased survival compared with patients older than 50. The objective of this analysis was to determine, from a large database of patients with early-stage breast cancer, if the Recurrence Score(®) result (Oncotype DX(®), Genomic Health, Inc, Redwood City, CA, USA) provided clinic...

We report here a 44-year-old Moroccan man with resectable gastric adenocarcinoma with overexpression of human epidermal growth factor receptor 2 (HER2) by immunohistochemistry who was treated with trastuzumab in combination with chemotherapy in perioperative setting. He received 3 cycles of neoadjuvant chemotherapy consisting of trastuzumab, oxaliplatin, and capecitabine. Afterwards, he receive...