The concept of rigid reference frame and of constricted spatial metric, given in the previous work [Clas. Quantum Grav. 21, 3067,(2004)] are here applied to some specific space-times: In particular, the rigid rotating disc with constant angular velocity in Minkowski space-time is analyzed, a new approach to the Ehrenfest paradox is given as well as a new explanation of the Sagnac effect. Finall...

Most naturally occurring mutants of the retinoblastoma (RB) protein contain large deletions or truncations. The small cell lung carcinoma cell line H209 contains a normal-sized but unphosphorylated RB protein (Hensel et al., Cancer Res., 50: 3067-3072, 1990), which fails to form a complex with SV40 T antigen, suggesting that the RB gene of H209 may contain a subtle mutation. To define this muta...

Abstract Background and Aims Alport Syndrome (AS) is caused by pathogenic variants in COL4A3, COL4A4 & COL4A5 genes. The clinical course of AS can be highly variable, depending on gene affected, mutation type Male (M) or Female (F) sex. Proteinuria associated with worse prognosis. Previous genotype-phenotype correlation studies have shown protein length altering are a more severe phenotype ...

We aimed to explore the clinical relevance of a multicentre, pragmatic randomised trial antipsychotic reduction in people diagnosed with schizophrenia or psychosis The sample recruited for study (n = 69 people) was compared population patients an eligible diagnosis undergoing treatment same service 3067 people), using routinely-collected, anonymised data. found resemble wider terms number past ...