نتایج جستجو برای: 3351 nmg and bending resistance

تعداد نتایج: 16900694  

Journal: :Tidsskrift for Den norske legeforening 2014

2015
Madhusudhan Kollareddy Elizabeth Dimitrova Krishna C. Vallabhaneni Adriano Chan Thuc Le Krishna M. Chauhan Zunamys I. Carrero Gopalakrishnan Ramakrishnan Kounosuke Watabe Ygal Haupt Sue Haupt Radhika Pochampally Gerard R. Boss Damian G. Romero Caius G. Radu Luis A. Martinez

Mutant p53 (mtp53) is an oncogene that drives cancer cell proliferation. Here we report that mtp53 associates with the promoters of numerous nucleotide metabolism genes (NMG). Mtp53 knockdown reduces NMG expression and substantially depletes nucleotide pools, which attenuates GTP-dependent protein activity and cell invasion. Addition of exogenous guanosine or GTP restores the invasiveness of mt...

2009
Eric A. Bergshoeff Olaf Hohm Paul K. Townsend

We explore the space of static solutions of the recently discovered three-dimensional ‘New Massive Gravity’ (NMG), allowing for either sign of the Einstein-Hilbert term and a cosmological term parametrized by a dimensionless constant λ. For λ = −1 we find black hole solutions asymptotic (but not isometric) to the unique (anti) de Sitter vacuum, including extremal black holes that interpolate be...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سیستان و بلوچستان 1390

seismic retrofit strategies have been developed in the past few decades following the introduction of new seismic provisions and the availability of advanced materials and methods. it can be observed that new approaches to deal with more lateral forces are more innovative and more energy absorbent. in line with this, there is a growing trend toward the use of steel shear walls as a system with ...

2015
Kristin Luehders Noriaki Sasai Hongorzul Davaapil Maiko Kurosawa-Yoshida Hitoshi Hiura Tara Brah Shin-ichi Ohnuma

Small leucine-rich repeat proteoglycan (SLRP) family proteins play important roles in a number of biological events. Here, we demonstrate that the SLRP family member Asporin (ASPN) plays a crucial role in the early stages of eye development in Xenopus embryos. During embryogenesis, ASPN is broadly expressed in the neuroectoderm of the embryo. Overexpression of ASPN causes the induction of ectop...

2014
Donika Gallina Christopher Zelinka Andy J. Fischer

Identification of the signaling pathways that influence the reprogramming of Müller glia into neurogenic retinal progenitors is key to harnessing the potential of these cells to regenerate the retina. Glucocorticoid receptor (GCR) signaling is commonly associated with anti-inflammatory responses and GCR agonists are widely used to treat inflammatory diseases of the eye, even though the cellular...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد علوم دارویی - پژوهشکده علوم 1392

purpose a metabolic abnormality such as obesity is a major obstacle in the maintenance of the human health system and causes various chronic diseases including type 2 diabetes, hypertension, cardiovascular diseases, as well as various cancers. this study was designed to summarize the recent scientific knowledge regarding the anti-obesity role of curcumin (diferuloylmethane), which is isolated f...

Journal: :جنگل و فرآورده های چوب 0
حسین رنگ آور دانشگاه شهید رجایی منوچهر عباسی هنرآموز هنرستان فنی

this study was aimed to investigate the bending moment and stress (inner and outer corners) in lshaped biscuit joint made of solid wood, particleboard and medium density fiberboard (mdf). for this purpose, l-shaped joints made of beech and fir, particleboard and mdf by biscuit size numbers of 0 (47×15×3.8 mm), 10 (53×19×3.8mm) and 20 (60×23×3.8mm). bending moment and stress carrying capacity of...

Journal: :Journal of High Energy Physics 2016

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