background burn is still one of the most devastating injuries in emergency medicine while improvements in wound healing knowledge and technology have resulted into development of new dressings. this study was undertaken to evaluate the healing effect of licorice in pseudomonas aeruginosa infected burn wounds of experimental rat model. methods one hundred and twenty female sprague-dawley rats we...

Background Most of the current models for experimental burns pose difficulties in ensuring consistency and standardization. Aim of Study We aimed to develop an automated, reproducible technique for experimental burns using steam-based heat transfer. Methods The system developed for steam exposure was based on a novel, integrated, computer-controlled design. Three groups of rats were exposed...

BACKGROUND Burn-induced inflammation leads to impaired immune responses resulting in increased morbidity and mortality. T-cells are central in the immune response and circulating CD4 and CD8 T-cells have been used to evaluate immune status; however, the role of these T-cell subsets in the burn wound is unknown. METHODS Male C57BL/6 mice were subjected to a major 3rd degree scald burn or sham ...

introduction: the aim of this work was to evaluate the effects of four different concentrations of aloe vera extract on healing of second degree burns in male wistar rats. materials and methods: by an experimental study 42 male wistar rats were divided into 7 equal groups. the burn injury was made on the back of all rats, according to standard methods. the burned areas in the group1: were left ...

BACKGROUND Burn injuries can have adverse effects on quality of life of patients and can disturb their physiological, psychological, social and spiritual well-being. This study aimed to investigate the effect of multimedia self-care program on quality of life in burn patients. METHODS This Randomized controlled clinical trial was conducted from November 2015 to December 2016. The samples were...

BACKGROUND Burn is still one of the most devastating injuries in emergency medicine while improvements in wound healing knowledge and technology have resulted into development of new dressings. This study was undertaken to evaluate the healing effect of licorice in Pseudomonas aeruginosa infected burn wounds of experimental rat model. METHODS One hundred and twenty female Sprague-Dawley rats...

BACKGROUND Burn is the most devastating condition in emergency medicine leading to chronic disabilities. This study aimed to compare the effect of Lithospermum officinale, silver sulfadiazine and alpha ointments on healing of burn wounds in rat. METHODS Ninety-five rats were divided into 5 groups. Group 1 just underwent burn injury, and groups 2-5 received alpha ointment, silver sulfadiazine ...

BACKGROUND Autophagy plays a major role in myocardial ischemia and hypoxia injury. The present study investigated the effects of autophagy on cardiac dysfunction in rats after severe burn. METHODS Protein expression of the autophagy markers LC3 and Beclin 1 were determined at 0, 1, 3, 6, and 12 h post-burn in Sprague Dawley rats subjected to 30% total body surface area 3rd degree burns. Autop...