allergic rhinitis (ar) is an ige-mediated upper airway disease, and its impact on asthma has been widely recognized. protein tyrosine phosphatase non-receptor 22 (ptpn22) gene and the cytotoxic t-lymphocyte–associated antigen 4 (ctla-4) gene polymorphisms have been reported to be associated with several immune-related diseases. here we investigated the reffect of these two genes’ polymorphisms ...

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Studies suggest certain stimuli like apoptosis behind the aberrant expression of circulating specific auto-antibodies in Type-1 diabetic patients. In present study, we investigated whether Streptozotocin (a diabetogenic compound) induced Rat RINm5f Insulinoma cells can expose immunogenic cryptic antigens. A time course treatment with 4 mM revealed 6hrs as minimal period to induce without much e...

SSEA-4 antigen can be mainly found in embryos and embryonic stem cells. However, its expression has been observed also adult progenitor cells, or even some differentiated Moreover, we a considerable number of positive (SSEA-4+) cells within the rabbit peripheral blood bone marrow mononuclear (PBMCs BMMCs) our previous study. Since no information about such anywhere literature, aim this study wa...