نتایج جستجو برای: 454
تعداد نتایج: 4949 فیلتر نتایج به سال:
O objetivo deste trabalho foi avaliar a freqüência das metástases (M) ocultas, bilateralidade da neoplasia e os custos do estadiamento em mulheres com câncer de mama operável. Assim, realizamos no Instituto Nacional Câncer - Rio Janeiro Brasil, estudo retrospectivo (60 meses) avaliando 454 pacientes matriculadas operável mama, analisando seu clínico (Ec). Este constou exame físico, mamografía, ...
Silybin, a major pharmacologically active compound in silymarin, has been widely used in combination with other prescriptions in the clinic to treat hepatitis and a host of other diseases. Previous studies suggested that silybin is a potential inhibitor of multiple drug-metabolizing enzymes (DMEs); however, the in vitro to in vivo translation and the mechanisms involved remain established. The ...
BACKGROUND The impact of raltegravir-resistant HIV-1 minority variants (MVs) on raltegravir treatment failure is unknown. Illumina sequencing offers greater throughput than 454, but sequence analysis tools for viral sequencing are needed. We evaluated Illumina and 454 for the detection of HIV-1 raltegravir-resistant MVs. METHODS A5262 was a single-arm study of raltegravir and darunavir/ritona...
Background: The main goal of Joint Genome Institute’s (JGI) Microbial Genome Program is to deliver finished microbial genomes faster, cheaper and better quality. Traditional method of producing multiple subclone libraries and Sanger reads is costly and also time consuming. 454 Life sciences has recently developed a highly scalable, highly parallel high throughput system which does not require t...
Sequencing of 18S rDNA clone libraries and 454-pyrosequencing are valuable methods used to describe microbial diversity. The massively parallel 454-pyrosequencing generates vast amounts of ribosomal sequence data and has the potential to uncover more organisms, even rare species. However, the relatively short sequence lengths of ∼500 bp are suboptimal for taxonomic annotation and phylogenetic a...
De novo assembled transcriptomes, in combination with RNA-Seq, are powerful tools to explore gene sequence and expression level in organisms without reference genomes. Investigators must first choose which high throughput sequencing platforms will provide data most suitable for their experimental goals. In this study, we explore the utility of 454 and Illumina sequences for de novo transcriptom...
SUMMARY Scaffolded and Corrected Assembly of Roche 454 (SCARF) is a next-generation sequence assembly tool for evolutionary genomics that is designed especially for assembling 454 EST sequences against high-quality reference sequences from related species. The program was created to knit together 454 contigs that do not assemble during traditional de novo assembly, using a reference sequence li...
With the progress of technology, virtual reality technology plays a key role in many domains and has great potential and applied prospects. Virtual campus is the reappearance of a real campus’s scene by applying virtual reality technology. This technology is aimed to the construction and propaganda of campus. But in the course of construction of the three-dimensional virtual campus scene, owing...
Mycoplasma pneumoniae type 2 strain FH was previously sequenced with Illumina (FH-Illumina) and 454 (FH-454) technologies according to Xiao et al. (2015) and Krishnakumar et al. (2010). Comparative analyses revealed differences in genomic content between these sequences, including a 6-kb region absent from the FH-454 submission. Here, we present a complete genome sequence of FH sequenced with t...
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