Do Wages Really Compensate for Risk Aversion and Skewness Affection? Utility theory suggests that foreseeable risk should increase the compensation for work. This paper expands on this notion: on basis of utility theory, people should care not only about risk but also about the skewness in the distribution of the compensation paid. In particular, because the degree of risk aversion ought to dec...

A rice cDNA, OsDEP1, encoding a highly cysteine (Cys)-rich G protein γ subunit, was initially identified as it conferred cadmium (Cd) tolerance on yeast cells. Of the 426 aa constituting OsDEP1, 120 are Cys residues (28.2%), of which 88 are clustered in the C-terminal half region (aa 170-426). To evaluate the independent effects of these two regions, two truncated versions of the OsDEP1-express...

Background: Loss of hearing is a non-visible disability (NVD) and the second most common congenital pathology. Apart from hearing loss, further disability in these domains has been reported like development of language, speech, cognition, and other evolving domains. These can be prevented by early identification and intervention. The aim of this study was to assess the outcomes of neonatal hear...

CRM66 (cross-reactive 66 kDa protein) is an inactive mutant form of Pseudomonas aeruginosa exotoxin A that has been isolated from a mutant strain of P. aeruginosa derived from nitrosoguanidine-based mutagenesis. The mutation within this enzyme toxin was previously identified as H426Y and it was shown to possess significantly reduced enzymic activity. Furthermore, it was previously suggested tha...

We report the detection of short period oscillations in the hot subdwarf B (sdB) star PG 1613+426 from time-series photometry carried out with the 91-cm Cassegrain telescope of the Catania Astrophysical Observatory. This star, which is brighter than the average of the presently known sdB pulsators, with B = 14.14 mag, has T eff = 34 400 K and log g = 5.97, its position is near the hot end of th...

In the phase III KEYNOTE-426 study, pembrolizumab + axitinib showed significant improvement in OS, PFS, and ORR vs sunitinib patients with RCC. This analysis assessed subsequent treatment enrolled KEYNOTE-426.