Fischer 344 rats were treated with 0, 100, 500, 2500, or 12,500 ppm di(2-ethylhexyl)phthalate (DEHP) in the diet for up to 104 weeks. Blood and urine were analyzed at weeks 26, 52, 78, and 104 from 10 animals per sex per group. Survival was slightly but not statistically reduced for rats receiving 12,500 ppm DEHP. Body weights and food consumption were significantly reduced for rats receiving t...

SCOPE The long-term effect of exposure to relevant dietary levels of genistein (GEN) on estrogen receptor-positive (ER+) human breast cancer (MCF-7) progression after GEN withdrawal in athymic mice xenograft model was studied. MATERIALS AND METHODS Feeding studies were conducted to determine the estrogenic effect of diets on MCF-7 tumor growth: (1) implantation (19 weeks) and withdrawal (6 we...

Long-term exposure of rodents to propylene oxide (PO) induced inflammation, respiratory cell hyperplasia, and nasal tumors at concentrations >/= 300 ppm, suggesting a possible role for cytotoxicity and compensatory cell proliferation in PO carcinogenesis. In this study, the effects of PO exposure on histopathology and cell proliferation in nasal and hepatic tissues were studied in male F344 rat...

Cenococcum graniforme, Suillus luteus, Thelephora terrestris, and three isolates of Pisolithus tinctorius were cultured on modified Melin-Norkrans medium at pH 3.4 and adjusted to 0 to 500 ppm (0 to 500 mug/ml) of aluminum or manganese sulfate. Except for T. terrestris, which was intolerant of aluminum at 150 and 250 to 500 ppm, and P. tinctorius isolate 250, which was intolerant of aluminum at...

Two experiments were conducted to evaluate the responses to carbadox and Cu additions in the postweaning diet of swine. The first trial contained 470 pigs in five replicates in a 2 x 5 factorial arrangement in a randomized complete block design. Weanling pigs 4-wk of age were fed diets containing 0 or 55 ppm carbadox and 0, 125, 250, 375 or 500 ppm Cu for a 5-wk period. Copper levels of 125 and...

Nasal, respiratory, reproductive and developmental toxicities of propylene oxide (PO) were examined by exposing male and female Sprague-Dawley rats to PO vapor by inhalation at a concentration of 0 (control), 125, 250, 500 or 1,000 ppm for 6 h/d, 7 d/wk, during a 5- to 6-wk period, including premating, mating and postmating or gestation. The inhalation exposure to 1,000 ppm PO seriously affecte...

Three experiments involving 296 pigs were conducted to determine the related effects of copper sulfate and ferrous sulfide on performance and liver copper and iron stores of growing-finishing pigs, and the effect of ferrous sulfide on the depletion of copper from the liver. The dietary addition of 250 ppm copper alone improved growth rate by 9.2% (621 vs 678 g/day) and feed to gain ratio by 3.3...

An Egyptian, plant pathogenic Fusarium solani isolate was grown on cobalt concentrations of 0, 50, 200, 500, 800, and 1000 ppm. The isolate survived concentrations up to 800 ppm, however failed to grow at 1000 ppm. Morphology and elemental analysis of the isolate under the investigated Co concentrations were studied using Scanning electron microscopy (SEM) and energy dispersive X-ray microanaly...

The potential of microalgae as renewable energy feedstock for biofuel production is well recognized in developing countries and it is a large source of biomass for capturing CO2 on non-arable lands. In the current studies photobioreactor with 2 L capacity was used and operated with generator exhaust gases for algal CO2 sequestration. The reactor operated on generator exhaust gases with CO2 rang...