4,878,891 11/1989 Judy et al. .................................. 604/5 5,109,016 4/1992 Dixon et al. ..... ... 514/410 5,120,649 6/1992 Horowitz et al..... ... 435/173 5,232,844 8/1993 Horowitz et al. 435/173.1 5,238,940 8/1993 Liu et al. ......... ... 514/410 5,281,616 1/1994 Dixon et al. .. ... 514/410 5,407,808 4/1995 Halling et al. ... ... 435/34 5,484,778 1/1996 Kenney et al. .. ... 514/63...

51) Int. Cl." ...................... C12P 21/00; C12N 15/00; C12N 1/00; A61K 39/00 52 U.S. Cl. ................................... 435/68; 435/172.3; 435/253; 435/317; 514/8; 514/12; 530/350; 530/351; 530/395; 530/808; 424/85; 424/88; 536/27 58) Field of Search ................... 435/68, 70,240, 243, 435/253, 172.3, 317; 514/12, 8; 260/112.5 R; 935/9, 11-13, 65; 536/27; 424/88, 85; 530/350, 35...

Sec. 514.1 Applications. 514.4 Substantial evidence. 514.6 Amended applications. 514.7 Withdrawal of applications without prejudice. 514.8 Supplemental new animal drug applications. 514.11 Confidentiality of data and information in a new animal drug application file. 514.12 Confidentiality of data and information in an investigational new animal drug notice. 514.15 Untrue statements in applicat...

U.S. PATENT DOCUMENTS 3,930,022 12/1975 Hawk et al. ........................ 424/330 4,076,843 2/1978 Hauck et al. ........................ 424/330 4,087,545 5/1978 Archer et al. ....................... 424/283 4,101,677 7/1978 Dunnigan et al. .................. 424/330 4,163,063 7/1979 Cannon et al. ...................... 424/330 4,228,169 10/1980 Johnson et al. ..................... 424/258 4...

Department of Clinical Pharmacy and Biopharmaceutics, Mie University Graduate School of Medicine (K.I., Y.H., T.I., M.O.), Tsu, Mie 514-8507, Japan Department of Pharmacy, Mie University Hospital (K.I., T.E., Y.M., T.I., M.O.), Tsu, Mie 514-8507, Japan Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka (C.K.), Mie 513-8670, Japan Department of Pulmonary and Critica...

We recently reported on the physical characteristics of photo-triggerable liposomes containing dipalmitoylphosphatidylcholine (DPPC), and 1,2-bis (tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine (DC(8,9)PC) carrying a photo agent as their payload. When exposed to a low-intensity 514 nm wavelength (continuous-wave) laser light, these liposomes were observed to release entrapped calcein green ...

* Corresponding authors: Eric Rassart and Elsy Edouard Département des Sciences Biologiques, Université du Québec à Montréal, Case Postale 8888 Succursale Centre-ville, Montréal, QC, H3C-3P8, Canada. Phone: 1 514 987 3000 ext 3953 and 2054. Fax: 514 9874647. E-mail: [email protected] and [email protected] Blood First Edition Paper, prepublished online December 6, 2010; DOI 10.1182/blood-2...

http://dx.doi.org/10.1016/j.eswa.2014.04.008 0957-4174/ 2014 Elsevier Ltd. All rights reserved. ⇑ Corresponding author. Tel.: +1 514 848 2424x5382; fax: +1 514 848 3171. E-mail addresses: [email protected] (K. Sultan), bentahar@encs. concordia.ca (J. Bentahar), [email protected] (W. Wan), f_alsaqq@encs. concordia.ca (F. Al-Saqqar). Khalid Sultan, Jamal Bentahar ⇑, Wei Wan, Faisal...

19 20 21 22 Mailing Address: D. J. Ostry 23 Department of Psychology 24 McGill University 25 1205 Dr. Penfield Avenue 26 Montréal, QC, Canada H3A 1B1 27 Phone: 514 398 6111 28 Fax: 514 398 4896 29 E-mail: [email protected] 30 31 32 Number of words in manuscript: 12632 33 Number of figures: 8 34 35 36 37 38 39 40 41

17 Address to which correspondence should be sent: 18 C. Elaine Chapman 19 Département de physiologie 20 Université de Montréal 21 PO Box 6128, Succursale centre ville 22 Montréal, Québec H3C 3J7 23 Canada 24 25 Tel : 514-343-2304 26 Fax : 514-343-6113 27 e-mail : [email protected] 28 29 30 Running title: Tactile roughness perception 31 32