This study illustrates the process of enhancing phenolics synthesis in Spirulina maxima grown in Zarrouk’s medium supplemented with sodium nitrate (NaNO3) and or phenylalanine (L-PA), attaining highest production obtained in medium containing 3.77 g.L NaNO3 and 100 mgL -1 L-PA. HPLC profile showed the presence of phenolic acids and flavonoids predominantly with gallate, chlorogenate, cinnamate,...

A simple, rapid, precise and accurate spectrophotometric method has been developed for estimation of Bambuterol hydrochloride from tablet formulation. In methanol, Bambuterol showed absorbance in the visible range at 265 nm. Linearity was observed in the concentration range of 40240 μgmL-1 (r= 0.9990). The assay results were found to be in good agreement with label claim. The recovery studies w...

Article history: Received on: 03/04/2017 Accepted on: 08/05/2017 Available online: 30/08/2017 The main objective of the present study is to find an appropriate in-vitro therapy to overcome clinically isolated antibiotic-resistant Salmonella and Shigella species from cases of layer poultry farms suffering from purulent dysentery and diarrhea. The present study demonstrated chemical synthesis of ...

BACKGROUND Indian medicinal plants used in the Ayurvedic traditional system to treat diabetes are a valuable source of novel anti-diabetic agents. Pancreatic α-amylase inhibitors offer an effective strategy to lower the levels of post-prandial hyperglycemia via control of starch breakdown. In this study, seventeen Indian medicinal plants with known hypoglycemic properties were subjected to sequ...

The present study aimed at characterizing biological potentials of endophyte Aspergillus terreus JAS-2 isolated from Achyranthus aspera. Crude extracted from endophytic fungus JAS-2 was purified and chemically characterized by chromatographic and spectroscopic studies respectively. Spectral assignment of NMR (nuclear magnetic resonance) data, 1H proton and 13C carbon analysis along with FTIR da...

The standard for stability and quality of drugs for approval of marketing, are assured by testing and systematic evaluation using different analytical techniques. The drugs are tested in pharma analytical lab involving analysts associated spectra, chromatogram etc , and the results are analyzed leading to fixation of expiry dates. Once the drug crosses its expiry period, its potency is lost and...

The dried plant was extracted with dichloromethane and after defatting with hexane, transferred repeatedly on silica columns using dichloromethane-hexane and ethyl acetate-hexane as mobile phases. Finally the fractions were purified by high performance liquid chromatography using a Pack-Sil column and hexane: Ethyl acetate as mobile phase. The structures of the isolated compounds included: cycl...

Introduction: Garlic (Allium sativum) is widely used as a flavor-enhancing dietary ingredient and exhibits wide spectrum of pharmacological effects. This study aimed to investigate the therapeutic effects aqueous garlic extract explore bioactivity against 15-lipoxygenase (15-LOX) mediated inflammopathies. Methods: In this study, antioxidant (DPPH free radical scavenging assay reducing power ass...

Two novel methods are presented for the spectrophotometric determination of colchicoside (COLSID). Method A involves the reaction of COLSID with Fe(III) to form complex and method B is based on the reaction of the drug with NH2OH.HCl, the absorbances of which are measured at 458 nm and 395 nm respectively. The calibration graphs are found to be linear over 20.00-120.00 and 20.00-100.00 μgmL for...

AMR Lotfy Saber Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt. -------------------------------------------------------------------------------------------------------------------------------------------Abstract A rapid and accurate HPLC method has been developed for the determination of pioglitazone hydrochloride in tablets. Chromatographic analysis was perform...