TAK-648 is a PDE4 inhibitor with demonstrated preclinical antidiabetic properties. Our objective was to develop a translational pharmacokinetic/pharmacodynamic (PK/PD) model for human type 2 diabetes (T2D) dose prediction using HbA1c results from a db/db mouse study. Estimated parameters in combination with tPDE4i values calculated for the clinical roflumilast dose of 500 μg were used to transl...

In this paper, we present a low power hybrid low-density-parity-check (LDPC) decoder hardware implementing layered min-sum decoding algorithm for IEEE 802.11n Wireless LAN Standard. The LDPC decoder hardware, which has 27 check node datapaths and 24x162 variable node memory, is implemented in Verilog HDL and verified to work correctly in a Xilinx Virtex II FPGA. For 648 block length and 1/2 cod...

Cite this article: Greer TL (2013) Maintaining a Focus on Cognitive Function in the Treatment of Substance Use Disorders. J Addict Med Ther 1: 1001. *Corresponding author Tracy L. Greer, Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9119, USA, Tel: (214) 648-0156; Fax: (214) 648-0167; Email: tracy.greer@ utsouthwester...

The banana weevil (BW), Cosmopolites sordidus, is the main coleopteran pest of banana, causing up to 100% yield loss. In this study, we screened 20 isolates entomopathogenic fungi (EPF) for management BW. lab, eight Beauveria bassiana caused >50% mortality adult BW, whereas Metarhizium anisopliae and Isaria fumosorosea were less pathogenic. B. ICIPE 648, 660 273 most pathogenic, killing ≥80%...

Anil K. Agarwal, Ph.D. Division of Nutrition and Metabolic Diseases Center for Human Nutrition Department of Internal Medicine University of Texas Southwestern Medical Center 5323 Harry Hines Blvd., Dallas, TX 75390, U.S.A. Ph: 214-648-7685 Fax: 214-648-0553 E-mail: [email protected] http://www.jbc.org/cgi/doi/10.1074/jbc.M111.250449 The latest version is at JBC Papers in Press. P...

Jorge C. G. Ramirez, Lynn L. Peterson, Diane J. Cook, Dolores M. Peterson Department of Computer Science & Engineering University of Texas at Arlington PO Box 19015, Arlington, TX 76019-0015 Tel: 817-272-3620; Fax: 817-272-3784 [email protected] HIV Clinical Research Group Division of General Internal Medicine University of Texas Southwestern Medical Center 5323 Harry Hines Blvd, Dallas, TX 7...

Baran Sumer1, Jinming Gao2† †Author for correspondence 1Department of Otolaryngology, Head and Neck Surgery, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA Tel.: +1 214 648 3102; Fax: +1 214 648 2246; E-mail: baran.sumer@ utsouthwestern.edu 2Department of Pharmacology, Harold C Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 5...

Eduardo Lopez-Medina 1 and Andrew Y. Koh 2, * 1 Department of Pediatrics, Universidad del Valle and Centro de Estudios en Infectología Pediátrica, Cali, Colombia. 2 Departments of Pediatrics and Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA. * Corresponding Author: Andrew Y. Koh, Department of Pediatrics and Microbiology, University of Texas Southwestern Medi...

[This corrects the article on p. 648 in vol. 8, PMID: 28959205.].