OBJECTIVE To compare the adverse effects and treatment adherence between 2 months of rifampin plus pyrazinamide (2RZ) and 6 months of isoniazid (6H). BACKGROUND Patients with silicosis in Hong Kong are at high risk of acquiring tuberculosis. A previous study showed that treatment with 6H reduced the risk of silico-tuberculosis by one half. METHOD Patients with silicosis and a Mantoux skin t...

Photodynamic therapy (PDT) outcome depends on the conditions under which it is carried out. Maintaining the tumour tissue oxygen level is important for PDT efficacy and using a low fluence rate can improve outcome. In this work we studied the response of human nasopharyngeal carcinoma tumours in murine models to hypericin-PDT carried out under low fluence and fluence rate. A drug-light interval...

Six-hourly three-dimensional ensemble variational (3DEnVar) (6H-3DEnVar) data assimilation (DA) assumes constant background error covariance (BEC) during a six-hour DA window and is, therefore, unable to account for temporal evolution of the BEC. This study evaluates one-hourly 3DEnVar (1H-3DEnVar) six-hourly 4DEnVar (6H-4DEnVar) methods analyses forecasts hurricanes with rapidly evolving Both ...

The genetic modification of cells to develop cell-based vaccines and to modulate immune responses in vivo can be risky and inconvenient to perform in clinical situations. A novel chelator lipid, nitrilotriacetic acid di-tetradecylamine (NTA-DTDA) that, via the NTA group has high affinity for 6His peptide, was used to directly anchor recombinant forms of T cell costimulatory molecules containing...

We reported, for the first time, the piezoresistance behaviors of single p-type 6H-SiC nanowires. The results suggest that present p-type 6H-SiC nanowires could be an excellent candidate for the fabrication of robust and reliable stress sensors.

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In the present work, antireflective sub-wavelength structures have been fabricated on fluorescent 6H-SiC to enhance the white light extraction efficiency by using the reactive-ion etching method. Broadband and omnidirectional antireflection characteristics show that 6H-SiC with antireflective sub-wavelength structures suppress the average surface reflection significantly from 20.5 % to 1.01 % o...

(57)Fe Mössbauer spectra have been recorded from the hexagonal (6H)- and trigonal (15R)- modifications of BaFeO2F and are compared with those previously recorded from the cubic form of BaFeO2F. The spectra, recorded over a temperature range from 15 to 650 K show that all of the iron in all the compounds is in the Fe(3+) state. Spectra from the 6H- and 15R-modifications were successfully fitted ...

An analytical model for lateral MOSFET that includes the effects of temperature variation in 4Hand 6H-SiC poly-type is presented in this paper. SiC shows a tremendous potential for high temperature electronics applications [1-4]. The model includes the effects of temperature variation on the threshold voltage, the carrier mobility, the body leakage current, and the drain and source contact regi...

4-amino-6-methyl- 1,2,4-triazine-3(2h)-thione-5-0ne (1) was condensed with propargyl bromidein the presence of sodium rnethoxide to afford 3-propargylmercapto- 4-arnino-6-rnethyl-1,2,4-triazin-5-one(2) . transformation of the latter to 8-dihydro- 3-methyl-7-methylene-4-oxo-6h-[1,2,4]triazino [3,4-b] [1,3,4] thiadiazine (3) was performed under the condition of palladium (ii) salt. ring closure o...