نتایج جستجو برای: 7 mmp
تعداد نتایج: 659328 فیلتر نتایج به سال:
Knowledge on the role of matrix metalloproteinases (MMPs) in adenoid cystic carcinoma (ACC) is limited. MMPs are capable degrading almost all extracellular and pericellular components to promote invasion metastasis. This study aimed evaluate immunohistochemical expression MMP-7, -8, -9, -15, -25 ACC relate results with clinicopathological factors survival. The included 68 patients minor salivar...
Abstract Objective To explore the advantages of urinary matrix metalloproteinase-7 (MMP-7) in evaluating renal tubular injury minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) patients compared with cystatin C (CysC) retinol binding protein (RBP). Methods Serum urine samples were collected from 20 healthy volunteers, 40 MCD FSGS patients. MMP-7 levels measured by enzyme...
BACKGROUND Matrix metalloproteinases (MMPs) contribute to left ventricular remodeling after myocardial infarction (MI). Specific causative roles of particular MMPs, however, remain unclear. MMP-7 is abundant in cardiomyocytes and macrophages, but MMP-7 function after MI has not been defined. METHODS AND RESULTS Wild-type (WT; n=55) and MMP-7-null (MMP-7-/-; n=32) mice underwent permanent coro...
The matrix metalloproteinases MMP-2, MMP-3, MMP-7, MMP-9, and MMP-13 are highly expressed in the tumor-bone microenvironment, and, of these, MMP-7 and MMP-9 were found to be localized to bone-resorbing osteoclasts in human breast-to-bone metastases. In a bid to define the roles of host-derived MMP-7 and MMP-9 in the tumor-bone microenvironment, the tibias of MMP-7 and MMP-9 null mice were injec...
matrix metalloproteinases (mmps) play an important role in gastric cancer (gc). accumulated evidence suggests that functional mmp-1 and mmp-7 gene polymorphisms are associated with several tumors. the aim of this study was to investigate two single nucleotide polymorphisms, mmp-1 -1607 1g/2g and mmp-7 -181 a/g, and their potential relationship with gc. we examined 246 gc patients and 252 age-a...
BACKGROUND Matrix metalloproteinases (MMP) are proteolytic enzymes that are essentially involved in turnover of the extracellular matrix (ECM). The aim was to investigate the diagnostic value of MMP-7 and MMP-10 as tumor markers in pleural effusion (PE) and evaluate the value of combining MMP-7, MMP-10 and carcinoembryonic antigen (CEA) assays as diagnostic aids for malignant cells. MATERIALS...
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