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The effect of 3-¿1-(p-chlorobenzyl)-5-(isopropyl)-3-tert-butylthioindol-2-yl-2, 2-dimethylpropanoic acid (MK-886), a leukotriene biosynthesis inhibitor, on Ca(2+) mobilization in Madin- Darby canine kidney cells has been examined by fluorimetry using fura-2 as a Ca(2+) indicator. MK-886 at 0.5 to 25 microM concentration dependently increased ¿Ca(2+)(i). The ¿Ca(2+)(i) increase comprised an imme...
1 Postgraduate, Civil Engineering, National Central University, No.300, Jhongda Rd., Jhongli City, Taoyuan County 32001, Taiwan ; Tel: +886-9-21-074897; E-mail: [email protected] 2 Associate Professor, Center for Space and Remote Sensing Research, National Central University, No.300, Jhongda Rd., Jhongli City, Taoyuan County 32001, Taiwan ; Tel: + 886-3-422-7151 ext 57619; Fax: +886-3-4254908...
and Laboratory of Regenerative Medicine, Department of Medical Research, and Department of Surgery, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan. Received: June 24, 2015 Accepted: March 16, 2016 Address reprint request and correspondence to: Ying-Hsien Kao, Laboratory of Regenerative Medicine, Department of Medical Research, and Po-Huang Lee, Department of Surgery, E-Da Hospital, No. 1, ...
Small cell lung cancer (SCLC) is one of the most aggressive types of cancer, yet the pathologic mechanisms underlying its devastating clinical outcome remain elusive. In this report, we surveyed 924 miRNA (miR) for their expressions in the formalin-fixed paraffin-embedded specimens from 42 patients with SCLC, and found that the downregulated miR-886-3p is closely correlated with the shorter sur...
No.1, Roosevelt Rd,. Sec. 4, TaGei, Taiwan 106, R.O.C. Phone: 886-2-2363525 1, Fax: 886-2-23678254, E-mail: [email protected] Shyh-Lin Tsao Institute of Electro-Optical Science and Technology, National Taiwan Normal University, No.88, Ting-ChouiRd,. Sec. 4, Taipei, Taiwan 116, R.O.C. Phone: 886-2-29350349, FAX: 886-2-29350382, E-mail: [email protected],tw Abstract Analysis of rhe minim...
زمینه و هدف: تا کنون در مطالعات مختلفی به بررسی موبیلیزاسیون سلول های بنیادی خونساز به منظور پیوند و اهمیت سیگنال های بتا آدرنرژیکی در القای این فرآیند، پرداخته شده است. با این وجود، اطلاعات کمی درباره نحوه اثر سیگنال های بتا آدرنرژیکی در موبیلیزاسیون سلول های بنیادی خونساز ، موجود است. sdf-1 در موبیلیزاسیون سلول های بنیادی خونساز، نقش کلیدی ایفا می کند. این کموکاین توسط سلول های بنیادی مزانشیم...
Complex or large information technology (IT) implementations are typically managed as single programs composed of multiple projects. Program managers must be able to manage the interfaces of multiple interdependent projects to realize the goals of an IT implementation. However, the common problems of conflict and poor coordination often hinder the achievement of a program’s goals. Part of this ...
Background. Global myocardial ischemia reperfusion injury after heart transplantation is believed to impair graft function and aggravate both acute and chronic rejection episodes. Objectives. To assess the possible protective potential of MK-886 and 3,5-diiodothyropropionic acid DITPA against global myocardial ischemia reperfusion injury after heart transplantation. Materials and Methods. Adult...
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