A s my year as president of SNMMI gets underway, a continuing focus for nuclear medicine is development of a reliable, domestic supply of radioisotopes. 99mTc remains the most commonly used radioisotope worldwide— used in 20–40 million diagnostic procedures each year. Shortages of 99Mo (the parent of 99mTc), resulting from reliance in recent years on aging reactors, have led to major efforts ar...

background: 99mtc is a widely used radioisotope in nuclear medicine centers which is obtained by elution from mo-99/tc-99m generators. usually the generators are either supplied by the iran atomic energy agency or by private companies from foreign countries. in this study we have measured 99mo contamination in 99mtc elute from different generators in a period of one year. materials and methods:...

background: hot lab is a specially designed room in a nuclear medicine hospital where the radiopharmaceuticals are delivered, stored and prepared for dispensing. 99mo/99mtc-generator is the major source in the hot lab used for various medical imaging. it is important to maintain a standard for hot lab procedures to optimize the patient care and minimize radiation exposure to all nuclear medicin...

Background: Hot lab is a specially designed room in a nuclear medicine hospital where the radiopharmaceuticals are delivered, stored and prepared for dispensing. 99Mo/99mTc-generator is the major source in the hot lab used for various medical imaging. It is important to maintain a standard for hot lab procedures to optimize the patient care and minimize radiation exposure to all nuclear medicin...

Technetium-99m (99mTc) is one of the most desirable radionuclides for external imaging in diagnostic nuclear medicine, due to the emission of gamma ray of optimal energy (140 keV), a suitable half-life (6 h), and availability from 99Mo-99mTc generator systems. In addition, development of 99mTc radiopharmaceuticals for tumor imaging paves the way for therapeutic radiopharmaceuticals with high en...

Lipophilic cationic technetium-99m-complexes are widely used for myocardial perfusion imaging (MPI). However, inherent uncertainties in the supply chain of molybdenum-99, the parent isotope required for manufacturing 99Mo/99mTc generators, intensifies the need for discovery of novel MPI agents incorporating alternative radionuclides. Recently, germanium/gallium (Ge/Ga) generators capable of pro...