The Taurus has a MacPherson strut type of suspension in the front and rear of the car, as shown in Figure 1. The various types of joints in the suspension are modeled with connector elements. These specialized elements provide an easy and versatile way to model physical mechanisms with point-to-point connections that can exhibit complex kinematic and kinetic relationships. A list of model joint...

Mice are themost commonly used species for non-clinical evaluations of drug efficacy against tuberculosis (TB). Unlike commonly used strains, C3HeB/FeJ mice develop caseous necrosis in the lung, which might alter the representation of drug efficacy in a way that is more like human TB. Because the development of such pathology requires time, we investigated the effect of infection incubation per...

During product development, design engineers often have the freedom to modify a number of parameters. However, any design modification requires validation to ensure the satisfaction of requirements for all load cases. With Abaqus for CATIA V5 (AFC), nonlinear finite element technology is made available within the CATIA environment, allowing design engineers to efficiently incorporate accurate s...

Electroencephalography (EEG) is used to obtain information about the electrical activity in the brain and is routinely used to diagnose neurological abnormalities. The inverse problem in EEG refers to the procedure of locating electrical sources in the brain from the extracranial electrical field measured on the scalp. The solution of the inverse problem requires the forward calculation of the ...

The structural analyses contained in this report were carried out under the direction of the National Transportation Safety Board Modeling Group with the participation of Professor Toshio Nakamura through an external contract with the State University of New York at Stony Brook. Added resources and expertise were acquired through a subcontract with Dassault Systèmes Simulia Corporation for assi...

The small intestine plays an important role in all aspects of pharmacokinetics, but there is no system for the comprehensive evaluation of small-intestinal pharmacokinetics, including drug metabolism and absorption. In this study, we aimed to construct an intestinal pharmacokinetics evaluation system and to generate pharmacokinetically functional enterocytes from human induced pluripotent stem ...

Proof. We will calculate the integral closure of A inside K. We begin with a more general discussion. Suppose C is an irreducible, affine curve, that is, C is some irreducible affine variety of dimension 1. Let A be the ring of regular functions on C, so that A is a noetherian domain of Krull dimension 1. Localization preserves the noetherian condition, as well as the domain condition. Thus, th...

The spread of multi-drug resistant tuberculosis necessitates the discovery of new classes of antibacterials and compounds that inhibit macromolecules involved in these resistant mechanisms. Thirty ethanol extracts from nineteen selected plants from Zimbabwe were screened against Mycobacterium aurum and Corynebacterium glutamicum using the agar disk diffusion method. These two organisms were use...

Coiled tubing is used in a variety of oil well operations including drilling, completions, and remedial activities. For each of these applications coiled tubing offers the benefits of reduced costs, speed, and reduced environmental impact. Coiled tubing possesses a limitation however, in that it may buckle in service. In this situation the tubing may be damaged, and operations may be delayed or...