To determine the peripheral mechanisms involved in thermal sweating during the hot summers in July before acclimatization and after acclimatization in September, we evaluated the sweating response of healthy subjects (n=10) to acetylcholine (ACh), a primary neurotransmitter involved in peripheral sudomotor sensitivity. The quantitative sudomotor axon reflex test (QSART) measures sympathetic C f...

For many low-altitude (<1500 m) residents, their travel itineraries may cause them to ascend rapidly to high (>2400 m) altitudes without having the time to develop an adequate degree of altitude acclimatization. Prior to departing on these trips, low-altitude residents can induce some degree of altitude acclimatization by ascending to moderate (>1500 m) or high altitudes during either continuou...

Pre-acclimatization at a convenient high-altitude location may represent an appropriate method before climbing a more hostile target mountain. The aim of the present field report was to demonstrate the effectiveness of such pre-acclimatizing applying the ‘‘climb high sleep low’’ maxim for a subsequent rapid ascent to almost 7000 m. After some pre-acclimatization in the Alps the authors flew to ...

Hiking and climbing in high mountains are becoming very popular during the last decade. High mountain climbing is mainly in the domain of skilled alpinists. On the other hand hiking is often organized by trekking agencies which took unskilled clients to very high mountains. The aim of the presents study is to emphasis the importance of the process of acclimatization to high altitude. Two studen...

The different types of response mechanisms that the organism uses when exposed to hypoxia include accommodation, acclimatization and adaptation. Accommodation is the initial response to acute exposure to high altitude hypoxia and is characterized by an increase in ventilation and heart rate. Acclimatization is observed in individuals temporarily exposed to high altitude, and to some extent, it ...

background adaptation is an important process for humans. children, who are physically or mentally disabled, impose special stresses on their families, parents and in particular on their mothers. objectives this study examines the relationship between the characteristics of mothers who have educable mentally retarded children, and their adaptation based on roy’s adaptation model. patients and m...

Cold acclimatization (4-5 degree C) is accompanied by 2-3 fold increase of brown adipose tissue (BAT). This rapid growth of interscapular BAT was studied after histamine depletion. In control rats maintained at room temperature (28 +/- 2 degree C) the BAT histamine content was 23.4 +/- 5.9 (mean +/- SD) microgram/g of tissue and cold acclimatization (5 +/- 1 degree C) produced a significant inc...

In order to understand the medical geography studies by Boudin, we analyze the differences that set him apart from the acclimatization theories defended during that same historical period by Isidore Geoffroy Saint-Hilaire. Each one of them represents a paradigmatic position in relation to the problem of acclimatization. To understand the difference between these models, we analyze the concept o...

The origin of brown adipocytes arising in white adipose tissue (WAT) after cold acclimatization is unclear. Here, we demonstrate that several UCP1-immunoreactive brown adipocytes occurring in WAT after cold acclimatization have a mixed morphology (paucilocular adipocytes). These cells also had a mixed mitochondrioma with classic "brown" and "white" mitochondria, suggesting intermediate steps in...

We studied sea-level residents during 13 days of altitude acclimatization to determine 1) altitude acclimatization effects on erythrocyte volume and plasma volume, 2) if exogenous erythrocyte volume expansion alters subsequent erythrocyte volume and plasma volume adaptations, 3) if an increased blood oxygen content alters erythropoietin responses during altitude acclimatization, and 4) mechanis...