نتایج جستجو برای: acetylsalicylic acid
تعداد نتایج: 747452 فیلتر نتایج به سال:
Protection of the small intestine from mucosal injury induced by nonsteroidal anti-inflammatory drugs including acetylsalicylic acid is a critical issue in the field of gastroenterology. Polaprezinc an anti-ulcer drug, consisting of zinc and L-carnosine, provides gastric mucosal protection against various irritants. In this study, we investigated the protective effect of polaprezinc on acetylsa...
The purpose of our study was to investigate the effects of different doses of acetylsalicylic acid on platelet aggregation. Among inpatients of the National Taiwan University Hospital, 236 cases of completed stroke and seven cases of reversible ischemic neurologic deficit that were diagnosed by computed tomography of the brain and that had not ingested acetylsalicylic acid or acetylsalicylic ac...
Diets containing 0.2% acetylsalicylic acid were fed to control and thiamine-deficient rats. Acetylsalicylic acid caused a significant decrease in body weight and adipose tissue weight in thiamine-deficient acetylsalicylic acidtreated but not in normal acetylsalicylic acid-treated rats. A large decrease in the total blood ketone bodies in thiaminedeficient acetylsalicylic acid-treated rats was o...
Diets containing 0.2% acetylsalicylic acid were fed to control and thiamine-deficient rats. Acetylsalicylic acid caused a significant decrease in body weight and adipose tissue weight in thiamine-deficient acetylsalicylic acidtreated but not in normal acetylsalicylic acid-treated rats. A large decrease in the total blood ketone bodies in thiaminedeficient acetylsalicylic acid-treated rats was o...
Acetylsalicylic acid and/or its metabolites are implicated to have various effects on metabolism and, especially, on mitochondrial function. These effects include both inhibitory and stimulatory effects. We investigated the effect of both combined and separate oral acetylsalicylic acid and acetaminophen administration at therapeutic doses on the urinary metabolite profile of human subjects. In ...
Low-dose acetylsalicylic acid has been widely used. We evaluated small bowel and gastric injuries during acetylsalicylic acid administration using video capsule endoscopy and gastroduodenal endoscopy. We also investigated blood flow using contrast-enhanced ultrasonography. Six healthy volunteers were enrolled in this preliminary study. The subjects were administered 100 mg of enteric-coated asp...
Incomplete endothelialization, blood cell adhesion to vascular stents, and inflammation of arteries can result in acute stent thromboses. The systemic administration of acetylsalicylic acid decreases endothelial dysfunction, potentially reducing thrombus, enhancing vasodilatation, and inhibiting the progression of atherosclerosis; but, this is weakened by upper gastrointestinal bleeding. This s...
OBJECTIVE To evaluate maternal and neonatal plasma concentrations of acetylsalicylic acid and salicylic acid and the neonatal endogenous prostanoid formation during low-dose aspirin prophylaxis (LDA; 100 mg daily) in pregnant women. METHODS Concentrations of acetylsalicylic acid and salicylic acid in maternal plasma after at least 4 weeks of LDA (n = 14) and in umbilical cord plasma of newbor...
A fixed-time incubation method for measuring acetylsalicylic acid esterase was improved by using a higher concentration of the substrate, acetylsalicylic acid, and an activator, Ca2+. The enzymatic activity in serum was 25-fold that measured by earlier methods. Inhibition studies showed a pattern similar to that reported for cholinesterase. Use of cholinesterase inhibitor in sample tubes for de...
Acetylsalicylic acid commonly known as aspirin is the most widely used drug in the world today. Its analgesic, antipyretic, and anti-inflammatory properties make it a powerful and effective drug to relive symptoms of pain, fever, and inflammation. The purpose of this experiment was to synthesize aspirin by reacting salicylic acid and acetic anhydride in the presence of phosphoric acid to form a...
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