Acne vulgaris is a common and chronic skin disease, and is a frequent source of morbidity for affected patients. Treatment of acne vulgaris is often difficult due to the multifactorial nature of this disease. Combination therapy, such as that containing clindamycin and benzoyl peroxide, has become the standard of care. Several fixed formulations of clindamycin 1% and benzoyl peroxide of varying...

Background: Acne vulgaris is a common skin disease that affects not only teenagers but also the general population. Although acne is not physically disabling, its psychological impact can be striking, contributing to low self-esteem, depression, and anxiety. As a result, there is a significant demand for effective acne therapies. Antihistamine is a widely used medication to treat several allerg...

IMPORTANCE Acne vulgaris is the most common skin condition affecting late adolescents across the globe. Although prior studies have evaluated epidemiologic patterns of acne vulgaris in various ethnicities and regions, adequate understanding of the worldwide burden of the disease associated with patients in their late adolescence (15-19-year olds) remains lacking. OBJECTIVE To assess the globa...

BACKGROUND Acne vulgaris causes erythematous papulopustular lesions in active stage and often leave behind residual scarring and pigmentation. Its onset in adolescence may add to the emotional and psychological challenges experienced during this period. AIMS To assess the impact of acne on the various psychosocial domains of daily life. MATERIALS AND METHODS This was a prospective, cross-se...

BACKGROUND Systemic and topical antimicrobials are effective in the treatment of inflammatory acne vulgaris; however, widespread use of these agents is becoming increasingly associated with the emergence of resistant pathogens raising concerns about microorganism resistance and highlighting the need for alternative nonantimicrobial agents for the treatment of acne. Nicotinamide gel provides pot...

Acne vulgaris remains one of the most common diseases afflicting humanity and it is the skin disease most commonly treated by physicians.[1] It is a disease of the pilosebaceous units, clinically characterized by seborrhea, comedones, papules, pustules, nodules and, in some cases, scarring.[2] Although easy to diagnose, the polymorphic nature of acne vulgaris and its varied extent of involvemen...

Background: The studies on Acne vulgaris conducted in many parts of the world show that it is very common in adolescents but little is known from Nepal. Objectives: To assess knowledge and attitude regarding Acne vulgaris among school students. Methods and Materials: This was a descriptive study conducted among 100 students of class 9 & 10 of Kumudini Homes Higher Secondary School, Pokhara, Nep...

Acne vulgaris as an inflammatory disease, with an excessive production of subdermal fat, modifies the dynamics of the bloodstream, and consequently temperature, on the affected skin zone. A high percentage of this heat interchange is manifested as electromagnetic radiation with far-infrared wavelengths, which can be captured through a thermal imaging camera. A technique based on thermal image a...

Resistin (RETN), recently found to be relevant to inflammation and inflammatory disorders. We, therefore, aimed to investigate the potential role of RETN gene polymorphism in pathogenesis of acne vulgaris with familial history. We investigated the RETN-420C/G polymorphism in 180 patients with acne vulgaris and 180 healthy individuals in a case-control association analysis. In this study, we als...

INTRODUCTION The aim of this study is to emphasize the therapeutic effect of thoracoscopic sympathicotomy performed at our clinic for facial/scalp hyperhidrosis or blushing on coincidental facial acne vulgaris based on previous reports indicating an association between the sympathetic nerve stimulus, epithelial melanocyte system and sebogenesis. MATERIAL AND METHODS The possible therapeutic e...