نتایج جستجو برای: acting antiviral

تعداد نتایج: 108524  

Journal: :Journal of Antivirals & Antiretrovirals 2012

Journal: :Current Treatment Options in Infectious Diseases 2017

Journal: :Journal of Shahid Sadoughi University of Medical Sciences 2019

2018
Barbara de M. Quintela Jessica M. Conway James M. Hyman Jeremie Guedj Rodrigo W. dos Santos Marcelo Lobosco Alan S. Perelson

Citation: Quintela BM, Conway JM, Hyman JM, Guedj J, dos Santos RW, Lobosco M and Perelson AS (2018) A New Age-Structured Multiscale Model of the Hepatitis C Virus Life-Cycle During Infection and Therapy With Direct-Acting Antiviral Agents. Front. Microbiol. 9:601. doi: 10.3389/fmicb.2018.00601 A New Age-Structured Multiscale Model of the Hepatitis C Virus Life-Cycle During Infection and Therap...

2016
Meghan E. Sise Jessica Wisocky Ivy A. Rosales Donald Chute Jacinta A. Holmes Kristin M. Corapi Jodie L. Babitt Jessica S. Tangren Nikroo Hashemi Andrew L. Lundquist Winfred W. Williams David B. Mount Karin L. Andersson Helmut G. Rennke R. Neal Smith Robert Colvin Ravi I. Thadhani Raymond T. Chung

Novel, all-oral interferon-free direct-acting antiviral agents have revolutionized the management of hepatitis C virus (HCV) infection by producing exceptional cure rates with minimal adverse events. While provocation or exacerbation of autoimmunity has been reported in HCV-infected patients receiving interferon, this phenomenon has not been reported in patients receiving interferon-free HCV th...

2017
Susana N. Asin Joel D Baines Sara Sobhy Kishta Sobhy Ahmed Kishta Reem El-Shenawy

Recent improvements have been made in the treatment of hepatitis C virus (HCV) infection with the introduction of direct-acting antiviral agents (DAAs). However, despite successful viral clearance, many patients continue to have HCV-related disease progression. Therefore, new treatments must be developed to achieve viral clearance and prevent the risk of HCV-related diseases. In particular, the...

2016
Sara Kishta Reem EI-Shenawy Sobhy Kishta Joel D Baines Sara Kishta Susana Asin

Recent improvements have been made in the treatment of hepatitis C virus (HCV) infection with the introduction of direct-acting antiviral agents (DAAs). However, despite successful viral clearance, many patients continue to have HCV-related disease progression. Therefore, new treatments must be developed to achieve viral clearance and prevent the risk of HCV-related diseases. In particular, the...

2016
Susana N. Asin Joel D Baines Sara Kishta Reem El-Shenawy Sobhy Kishta

Recent improvements have been made in the treatment of hepatitis C virus (HCV) infection with the introduction of direct-acting antiviral agents (DAAs). However, despite successful viral clearance, many patients continue to have HCV-related disease progression. Therefore, new treatments must be developed to achieve viral clearance and prevent the risk of HCV-related diseases. In particular, the...

2015
Anthony Cousien Viet Chi Tran Sylvie Deuffic-Burban Marie Jauffret-Roustide Jean-St'ephane Dhersin Yazdan Yazdanpanah

Background: Highly effective direct-acting antiviral (DAA) regimens (90% efficacy)are becoming

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