RATIONALE Central nervous system (CNS) involvement of graft versus host disease (GvHD) is a rare cause of CNS disorders after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Chronic CNS GvHD symptoms are heterogeneous and include cerebrovascular manifestations, demyelinating disease and immune-mediated encephalitis. CNS-Acute GvHD is not formally defined in literature. PATIENT...

Standards for the recognition of occupational diseases (ODs) in Korea were established in 1954 and have been amended several times. In 2013, there was a significant change in these standards. On the basis of scientific evidence and causality, the International Labour Organization list, European Commission schedule, and compensated cases in Korea were reviewed to revise the previous standards fo...

The abrupt onset of CNS symptoms in SLE patients presents a diagnostic and therapeutic challenge. As reported on a recent review of 323 SLE patients, the most common CNS presentations in descending order of frequency were headache, cerebrovascular disease, mood disorders, cognitive dysfunction, seizures, psychosis, anxiety disorder, and acute confusional state. [2] These symptoms may be either ...

Neuropeptide Y (NPY), a neuropeptide highly conserved throughout evolution, is present at high levels in the central nervous system (CNS), as well as in peripheral tissues such as the gut and cardiovascular system. The peptide exerts its effects via multiple receptor subtypes, all belonging to the G-protein-coupled receptor superfamily. Of these subtypes, the Y1 and the Y2 are the most thorough...

The central nervous system (CNS) tissues, including the brain, the eye, and the spinal cord, are immune-privileged, secluded from the circulation by a complex of barriers, and equipped with their own myeloid cell population, the resident microglia. Based on the classical perspective of immune-brain interactions and on the contribution of such interactions to the progression of multiple sclerosi...

SARS-COV-2 is a neurotropic virus that can trigger large-scale outbreak of neurological complications in the future. has neuroinvasive and properties allow it to enter central nervous system (CNS) infect neurons, accumulate tissue promote development delayed neurodegenerative processes. Among SARS-CoV-2 date, we distinguish group demyelinating lesions CNS. The paper describes two cases severe C...

Acute myelitis represents a major subset of acute non-compressive myelopathies. Acute non-compressive myelopathies include vascular, infectious, autoimmune, inflammatory, neoplastic and metastatic disorders. Acute myelitis can occur as an isolated inflammatory disorder, or as part of a multifocal CNS demyelinating disease such as acute disseminated encephalomyelitis, multiple sclerosis, neuromy...

how to cite this article: inaloo s, haghbin s, moradi m, dashti h, safari n. acquired cns demyelinating syndrome in children referred to shiraz pediatric neurology ward. iran j child neurol. 2014 spring; 8(2):18-23. objective incidence of cns acquired demyelinating syndrome (ads), especially multiple sclerosis (ms) in children, appears to be on the rise worldwide. the objective of this study wa...

Influenza is occasionally complicated by CNS disorders, in particular impairment of consciousness. Severe disorders encompass multiple, distinct syndromes manifesting acute encephalopathy, whereas mild disorders represent multiple, ill-defined neuropsychiatric syndromes. Acute encephalopathy is manifested with seizures and coma, with or without multi-organ involvement. The outcome varies from d...

Systemic Lupus Erythematosus (SLE) is a complex clinical syndrome which its components are less clearly recognized and includes heterogeneous demonstrations engaging both central and peripheral nervous system along with disabling effects. This disease is called "thousand faces" due to these heterogeneous demonstrations. This gap exists while 75% of adults and children with SLE may dea...