Background: Acute limb ischemia (ALI) is a sudden decrease in leg perfusion that threatens the viability of with symptom onset within 2 weeks. In peripheral artery disease (PAD) conditions, occlusion blood vessels can occur due to thrombosis or atherosclerotic plaque embolism, which called "acute on chronic ischemia". The development endovascular therapy has made this an important role restorin...

hashimoto's encephalopathy (he) is a rare condition characterized by atypical psychiatric and heterogeneous neurological manifestations such as acute cerebral ischemia, seizure, tremors, myoclonus, psychosis, depression, cognitive disorders, and fluctuating loss of consciousness. here, a case of 28 year-old man was reported who referred to the emergency department (ed) with different acute neur...

Objective(s): Morphine dependence (MD) potently protects heart against ischemia reperfusion (IR) injury through specific signaling mechanisms, which are different from the pathways involved in acute morphine treatment or classical preconditioning. Since opioid receptor density changes post cerebral ischemia strongly correlated with brain histological damage, in the present study, we tried to el...

BACKGROUND AND PURPOSE Ischemia on computed tomography (CT) is associated with subsequent stroke after transient ischemic attack. This study assessed CT findings of acute ischemia, chronic ischemia, or microangiopathy for predicting subsequent stroke after transient ischemic attack. METHODS This prospective cohort study enrolled patients with transient ischemic attack or nondisabling stroke t...

Splenic infarction occurs due to occlusion of splenic vessels that leads to splenic tissue ischemia and necrosis. There are several reports regarding splenic infarction in patients with acute myelogenous leukemia (AML). Herein, we report a case of acute promyelocytic anemia (AML-M3) who presented with abdominal pain and splenic infarction.

Summary Acute aortic dissection is an extremely serious condition with a high mortality risk. Symptoms may mimic other emergencies such as myocardial ischemia, often leading to misdiagnosis. A combination between coronary hypoperfusion and relatively rare, but when present it could be fatal. Early diagnosis correct surgical approach are essential success in those patients the rate requires impr...

Transient ischemic attack (TIA) is associated with a high 90-day risk of stroke. Recently, tools for identifying and triaging high-risk patients, rapid medical management, and access to specialist care have led to improved outcomes. One such tool, the age, blood pressure, clinical features, duration of transient ischemic attack, diabetes mellitus (ABCD2) score, uses clinical data to stratify pa...

background: nitric oxide synthase (nos) activity is increased during hypertension and cerebral ischemia. nos inactivation reduces stroke-induced cerebral injuries, but little is known about its role in blood-brain barrier (bbb) disruption and cerebral edema formation during stroke in acute hypertension. here, we investigated the role of nos inhibition in progression of edema formation and bbb d...

splenic infarction occurs due to occlusion of splenic vessels that leads to splenic tissue ischemia and necrosis. there are several reports regarding splenic infarction in patients with acute myelogenous leukemia (aml). herein, we report a case of acute promyelocytic anemia (aml-m3) who presented with abdominal pain and splenic infarction.

Background: Nitric oxide synthase (NOS) activity is increased during hypertension and cerebral ischemia. NOS inactivation reduces stroke-induced cerebral injuries, but little is known about its role in blood-brain barrier (BBB) disruption and cerebral edema formation during stroke in acute hypertension. Here, we investigated the role of NOS inhibition in progression of edema formation and BBB d...