OBJECTIVES To assess the detectability of a low-signal-intensity line within adenomyosis lesions adjacent to the endometrium on apparent diffusion coefficient (ADC) maps, and to establish correlations between these lesions and their possible causes, and more particularly the hormonal changes and magnetic resonance (MR) factors. MATERIALS AND METHODS MR images were obtained from 110 patients w...

Figure 1. Demonstration of outlier detection based on a simulation data. (a) shows the noise-free peanut-shaped ADC spatial profile obtained from a 2D tensor. (b) depicts results with an extreme outlier. The dotted line represents the measurement data, while the solid line is the fitted ADC profile. (c) shows the error map between the measured ADC and the fitted ADC signals. It clearly demonstr...

Mutations in the epidermal growth factor receptor (EGFR) gene are commonly observed in non-small-cell lung cancer (NSCLC), particularly in tumors of adenocarcinoma (ADC) histology (NSCLC/ADC). Robust data exist regarding the prevalence of EGFR mutations in Western and Asian patients with NSCLC/ADC, yet there is a lack of data for patients of other ethnicities. This review collated available dat...

BACKGROUND AND PURPOSE Diffusion and perfusion MR imaging have been reported to be valuable in the diagnosis of acute ischemia. Our purpose was to ascertain the value of these techniques in the prediction of ischemic injury and estimation of infarction size, as determined on follow-up examinations. METHODS We studied 18 patients with acute ischemic stroke who underwent echo-planar perfusion a...

Fig. 1. MR imaging in the first 24 h after acute ipoxic–ischaemic brain damage. Axial apparent diffusion coefficient map shows a reduced ADC value (0.41) in posterior putamen and globus pallidus, and a high ADC value in anterior putamen and head of caudate nuclei (0.73), indicating the prevalence of T2 effect. The relatively high ADC value indicates chronic impairment of anterior portion of bas...

BACKGROUND AND PURPOSE We hypothesized that, in acute cerebral ischemic stroke, anisotropic diffusion increases if T2 signal intensity is not substantially elevated and decreases once T2 hyperintensity becomes apparent. Our purpose was to correlate fractional anisotropy (FA) measurements with the clinical time of stroke onset, apparent diffusion coefficients (ADC), and T2 signal intensity. ME...

Background: Pathological lesions usually replace normal components of the vertebral bone marrow including benign and malignant lesions, as well as, fractures, inflammatory and degenerative marrow process. DWI is considered to be a potential tool which can help in characterization of different bone marrow lesions by exploiting the structural differences of biologic tissue. Objective: To evaluate...

Therapies targeting the mitogen-activated protein (MAP) kinase pathway in melanoma have produced significant clinical responses; however, duration of response is limited by acquisition of drug resistance. Rational drug combinations may improve outcomes in this setting. We assessed the therapeutic combination of an antibody-drug conjugate (ADC) targeting the endothelin B receptor (EDNRB) with sm...

MATERIAL AND METHODS The study was of prospective-retrospective character. It was carried out at the AKH in Vienna (Austria), where 100 patients with focal liver lesions were included in the study. All patients underwent the routine MR sequences on appliances 1,5 and 3T (Siemens, Germany): T1, T2, HASTE, VIBE, and a DWI with three b values (b 50, b 300 b 600 s / mm2) and ADC map with ROI (regio...