normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : adhesions, as abnormal scared tissue, are common following gynecological operations and can cause chronic pelvic pain, infertility, poor outcomes of future surgeries, and intestinal obstruction. oxygen free radicals are known as one of the main causes of adhesion formation. this study is to evaluate the effect...

objective: to determine the preventive effects of local administration of simvastatin for postoperative intra-abdominal adhesion formation in animal model of rat . methods: in this experimental study, 32 wistar albino rats as the animal model of intra-abdominal adhesion formation were included. adhesions were induced in all the animals via abrasion of the peritoneal and intestinal surface durin...

  Background : Pseudomonas aeruginosa is one of important opportunistic pathogen, that cases serious infections . It produces many virulence factors, and this bacterium usually is resistance against antimicrobial agents.   Objective :The aim of this study was evaluate the effects of sub-MICs of essential oils of Mentha spicata and Cumminum cyminum on alginate production, biofilm formation, swim...

Platelet activation and adhesion to the site of vascular injury is a dynamic process comprising reversible and irreversible phases. Platelet adhesion typically occurs in a multi-step process similar to the selectin/integrin-mediated adhesion of neutrophils. This phenomenon is highly regulated and influenced by the cross-talk between platelets and injured endothelium. This cross-talk involves a ...

post operative adhesion formation is a very important clinical problem because of its complications such as pain, bowel obstruction, infertility and subsequent intra-operative complications. we aimed to investigate the effects of melatonin (me), as an agent acting against free radicals, on the prevention of adhesion formation. background: a number of 39 rats were randomly assigned into three gr...

  Objective- Mechanisms that decrease oxidative stress and enhance peritoneal fibrinolysis reduce adhesions. N-acetyl-L-cysteine (NAC) is an antioxidant whose effect on peritoneal fibrinolysis in large animal model has not been established. The aims of this study were to investigate the ability of NAC to decreased adhesion in stablished model of serosal trauma in sheep. Design- Expe...

Background & aims: Adhesion and fibrotic bands formation is one of the most important post-surgical complication in pelvic and abdominal surgeries. Major studies in prevention of adhesion formation have based on antioxidant and anti-inflammatory agents. Silymarin, Silybum marianum extract contains compounds with antioxidant, anti-inflammatory and fibrinolytic activities thus could reduce adhesi...

Background: Postoperative peritoneal adhesion bands are one of the most common complications caused by foreign material.  Objective: To investigate the effect of colchicine on talc-induced peritoneal adhesion bands. Method: Adhesion bands were induced in 30 short hair England Guinea pigs by introduction of talc-saline solution (10 mL, 10%) into the peritoneal cavity.  Afterwards, the pigs were ...

Chitosan bears numerous properties, such as biocompatibility, biodegradability and non-toxicity making it suitable for use in different biomedical fields. Zinc (Zn) is required for fibroblasts proliferation and collagen synthesis as essential elements of wound healing. Its nanoparticles are well known for their capability to enhance wound healing by cell adhesion and migration improvement throu...