The association of increased adrenocortical activity with carcinoma in certain site notably the bronchus, has been increasingly recognised in recent years (Allott; Skelton, i960; Bagshawe, i960). About fifty cases have been reported to date. It possible, however, that the association is not as rare as this figure would suggest, sin1; a number of these patients have not had the clinical features...

The effect of malnutrition on the adrenal cortex has not been well studied. Earlier reports suggested that malnutrition in man produced adrenocortical hypofunction (Zubiratn and Gomez-Mont, 1953), and more recent reports suggest normal function (Lurie and Jackson, 1962) and possibly hyperfunction of the adrenal cortex in malnourished infants (Alleyne and Young, 1966). The purpose of this study ...

The prognosis of pediatric adrenocortical carcinoma often depends on prompt diagnosis to begin treatment before metastatic progression. We discuss a girl who presented at 8 months of age with virilization, which was thought to be due to exposure to a topical testosterone preparation being used by her father. Her testosterone level did not decrease promptly after her father discontinued the medi...

Limited data are available about mitotane-nduced hyperlipidemia. We retrospectively analyzed lipid data in 38 patients with adrenocortical carcinoma (ACC) who received mitotane therapy with emphasis on HDL cholesterol (HDL-c) and clinical predictors of lipid changes. At baseline, the mean levels of HDL-c, LDL-c, and triglycerides were 53.3 mg/dL, 114.4 mg/dL, and 149 mg/dL, respectively. HDL-c,...

PURPOSE : To develop a clinical prediction model to predict a clinically relevant adrenal disorder for patients with adrenal incidentaloma. MATERIALS AND METHODS : This retrospective study is approved by the institutional review board, with waiver of informed consent. Natural language processing is used for filtering of adrenal incidentaloma cases in all thoracic and abdominal CT reports from...

Adrenal diseases comprise for a variety of medical endocrine issues, ranging from partial or complete gland insufficiency, to several kinds of adrenal hyperfunction, either of congenital or neoplastic etiology. For hypofunction of the adrenals (partial or complete) the treatment of choice is medical; the mainstay of treatment is hydrocortisone. Patients with congenital adrenal hyperplasia cause...

We study Fourier and Laplace transforms for hyperfunctions with values in a complex locally convex Hausdorff space. Since any hyperfunction wide class of spaces can be extended to hyperfunction, this gives simple notions asymptotic vector-valued hyperfunctions, which improves the existing models Komatsu, B\"aumer, Lumer Neubrander Langenbruch.

During a period of IS years from 1975 to 1989, eleven children with adrenocortical tumors were managed with relatively favorable results in our center. Despite its rarity in the pediatric age group, our series is one of the largest reported in the literature in the given period of time. All of our 11 patients presented with hyperfunction of the adrenal cortex. Virilization alone was the mo...