Die biokatalytische Oxidation acylierter Hydroxylamine ermöglicht die direkte und selektive Einführung Stickstoff-haltiger funktioneller Gruppen durch Aktivierung allylischer C-H-Bindungen. Durch Verwendung von entweder Laccasen oder einem Enzympaar aus Oxidase Peroxidase mit Luft als terminalem Oxidationsmittel erfolgt formale Dehydrierung N-Hydroxycarbamaten Hydroxamsäuren, wodurch unter über...

......................................................................................................................................... v Introduction ................................................................................................................................... 1 Saccharomyces cerevisiae as a model system ......................................................................

The L( +)-lactate dehydrogenase (EC 1.1.1.27) of Alcaligenes eutrophus catalyzes the NADH-dependent reduction of pyruvate and a few other 2-oxoacids. The K,,, values for NADH, NAD, pyruvate and L( +)-lactate are 0.075 mM, 0.130 mM, 0.820 mM and 7.10 mM, respectively. The reaction follows a rapid equilibrium ordered bi-bi mechanism and involves the formation of a dead-end EBQ complex. The compet...

Against 182 anaerobe and 241 aerobe strains obtained from diabetic foot infections, doripenem was the most active carbapenem against Pseudomonas aeruginosa (MIC(90), 2 microg/ml), more active than imipenem against Proteus mirabilis, and ertapenem was more active against Escherichia coli and Klebsiella spp. The MIC(50) and MIC(90) values were < or =0.125 microg/ml for methicillin-sensitive Staph...

The majority of modern organisms, including many prokaryotes, are aerobes;1 that is, they use molecular oxygen as the terminal electron acceptor for energy generation. Although nearly every redox gradient in nature appears to be utilized by one organism or another,2-4 aerobic metabolism predominates, in large part due to the highly exergonic nature of the four-electron, four-proton (4e/4H+) red...

s of papers 55 allowed by either oxygen or MAP (not different from each other). Of the treatments evaluated, CO2 allowed the least growth of psychrophiles. Proliferation of E. coli and aerobes was the greatest when packaged in air after 14 d, while CO2 packaging resulted in the least growth. These data suggest that O2 may be a preferred environment, which actually reduced Campylobacter recovery...

The edentulous ridge's mucosa presents various histological aspects and different histoenzymatic equipment. These aspects are determined by constitutional factors (genetic, nutritional), as well as by age and by the associated pathology. The purpose of this paper is to evidentiate, through histochemical techniques, the aerobe (NADH2-cytochrome-c reductase) and anaerobe (lactatdehydrogenase) oxi...