PURPOSE To determine the prevalence of early and late-stage age-related macular degeneration (ARMD) and its association with risk factors such as age, gender, smoking, body mass index, hypertension and diabetes history, cataracts and pseudophakia. DESIGN Population-based cross-sectional study in an elderly Japanese-Brazilian population from Londrina (Paraná, Brazil). METHODS The study inclu...

Age-related macular degeneration (ARMD) is a multifactorial and polygenic disease and is the main cause of vision loss in developed countries. The environmental factors of ARMD can modify prevalence and incidence of this disease. This article is a review of the main environmental factors currently recognized as at risk or protective factor for ARMD. Modification of these factors is of crucial i...

Abstract Background The purpose of this study is to evaluate the influence anti-vascular endothelial growth factor (VEGF) in appearance or progression epiretinal membranes (ERMs) age-related macular degeneration (ARMD) and investigate confounding factors causing ERMs. Methods Seventy-six eyes that were treated for more than 36 months from first anti-VEGF injection assessed. Binary logistic regr...

background: age-related macular degeneration (amd) is one of the leading causes of visual loss among people aged 65 yr and older. the pathophysiology of amd is poorly understood. the purpose of this study was to evaluate the relationship between serum lipid concentrations and age-related macular degeneration. methods: in this case-control study, total cholesterol (tch), low density lipoprotein ...

PURPOSE To develop a systematic method for identifying and grading age-related macular degeneration (ARMD) in human donor eyes, postmortem fundus appearance was compared with histopathologic assessment in eyes with a spectrum of age-related macular change. METHODS Eyes without grossly visible, late ARMD were obtained from 8 cancer patients and 26 donors older than 50 years. Postmortem fundus ...

AIMS To evaluate alteration of plasma malondialdehyde (MDA) and nitric oxide (NO) levels in patients with exudative age related macular degeneration (ARMD). METHODS Plasma nitrite plus nitrate concentrations as an index of plasma NO levels and plasma MDA level as a marker of lipid peroxidation were measured in patients with exudative ARMD and age and sex matched healthy subjects. RESULTS Si...

Age-related macular degeneration is an eye disease, that gradually degrades the macula, a part of the retina, which is responsible for central vision. ARMD occurs in one of the two types, 1. Dry ARMD and 2. Wet ARMD. The purpose of this paper is to diagnose the retinal disease ARMD. The extent of the disease spread in the retina can be identified by extracting the features of the retina. Detect...

Aim: To evaluate the histological changes and immune response of conjuctiva in patients (pts) with lo S.S. Materials and Methods: We studied conjunctiial biopsies from 15 pts with I0 S.S. and 2 normal controls using 1) paraflfn section screening for the quality of conjunctival epithelium (CE), the number of goblet cells (GC) and the degree of inflammation, 2) Mo-abs and Pabs to: Tlymphocytes, T...

Introduction: Subretinal hemorrhage is most commonly associated with choroidal neovascular membrane secondary to age-related macular degeneration (ARMD). Case presentation: A case of submacular hemorrhage is described in a 69-year-old male with dry age-related macular degeneration (ARMD) hours after undergoing an uncomplicated, routine cataract surgery of the left eye. Methods and results: Fluo...