The effects of treatment with cortisol on the growth and alanine-a-ketoglutarate transaminase 1 activity of Walker carcinosarcoma 256 were studied. Similarly, the effects of other conditions known to enhance gluconeogenic activity, such as diabetes, fasting, and high protein intake, were investigated. Each of these conditions was previously shown to be associated with elevated activity of alani...

Keywords: Ocimum gratissimum Alanine transaminase Aspartate transaminase Albino rats Aqueous extract Toxicological effect.

The spectral shift from 420 to 338 nm when pure bacterial D-amino acid transaminase binds D-amino acid substrates is also exhibited in part by high concentrations of L-amino acids (L-alanine and L-glutamate) but not by simple dicarboxylic acids or monoamines. Slow processing of L-alanine to D-alanine was observed both by coupled enzymatic assays using D-amino acid oxidase and by high pressure l...

conclusions it seems that hp eradication per se might not affect lfc, lft, lipid profile, and insulin resistance in dyspeptic nafld patients. results one hundred (49 males) patients with the mean age of 43.46 (± 11.52) were studied. repeated measure anova showed a significant reduction in lfc, anthropometric measurements, and laboratory parameters (except for hdl) in the both groups during the ...

background & aim:cadmium is an important industrial and environmental pollutant. cadmium is one of the most toxic and carcinogenic heavy metals to organisms. this heavy metal mainly distributes to the liver and kidney in humans and animal and, causing acute hepatic injury. experimental: the ethanol extract of satureja hortensis l. (lamiaceae family), was evaluated for its activity against c...

Gene duplication is one of the major evolutionary mechanisms providing raw material for the generation of genes with new or modified functions. The yeast Saccharomyces cerevisiae originated after an allopolyploidization event, which involved mating between two different ancestral yeast species. ScALT1 and ScALT2 codify proteins with 65% identity, which were proposed to be paralogous alanine tra...

It has now been clearly established that pyridoxal phosphate serves as the coenayme of many transaminases. Several lines of evidence have indicated that the coenzyme acts alternately as acceptor and donar of amino groups, shuttling between the aldehydic (pyridoxal phosphate) and amino (pyridoxamine phosphate) forms (2-11). However, a detailed study of the kinetics of the transaminase reaction w...