Alcohol provokes different molecular pathways contributing to a clinically significant neurotoxicity in different brain areas. Affected cognition in alcoholics can influence both daily life functioning and alcohol craving management abilities. Preventing alcohol-induced neurotoxicity with different neuroprotective pharmacological interventions is receiving strong scientific backgrounds from pub...

background: in asia pacific (ap) region, the exact picture of the alcohol use problems has remained relatively obscure. in this study, the profile of alcohol consumption and alcohol related disorders in ap countries are presented.     methods: official statistics on average alcohol consumption (alcohol per capita consumption, apc), alcohol related health variables, income group and alcohol poli...

background: this review was performed to evaluate the trend of alcohol use, characteristics of consumers, alcohol use disorders and toxic alcohol intoxications in bangladesh. in addition, sources and sales figures of alcoholic beverages, and number of legal permits issued for alcohol consumption are reported and analyzed. methods: a narrative search was performed on available medical literature...

Background: Various medical, psychiatric and social problems affecting alcohol abuser tend to overshadow their oral health. From an epidemiologic viewpoint, chronic consumption of alcoholic beverages is associated with an increased risk for the upper gastrointestinal tract cancer, and tobacco and alcohol are regarded as the major risk factors for oral cancer. The objective of this presentation ...

Introduction Alcohol use disorder is a real public health problem in the world, it consists of pathological mode consumption which characterized by loss control and craving. Depressive alcohol are among most frequent mental pathologies often associated. The links between these two disorders can be several types: Induced Disorders, Primary Disorders Secondary Dependence. They also have two-way r...

objective(s): oxidative stress has been established as a key cause of alcohol-induced hepatotoxicity. licochalcone b, an extract of licorice root, has shown antioxidative properties. this study was to investigate the effects and mechanisms of licochalcone b in ethanol-induced hepatic injury in an in vitro study. materials and methods: an in vitro model of ethanol-induced cytotoxicity in brl cel...

background no study from india has examined pathways to care in alcohol using population systematically. objectives the present study aimed to understand the pathways to care among alcohol-dependent individuals seeking help at a tertiary care center. patients and methods it was a cross-sectional, observational study. a total of 58 subjects diagnosed with alcohol- dependence syndrome as per dsm-...

Objective(s): Oxidative stress has been established as a key cause of alcohol-induced hepatotoxicity. Licochalcone B, an extract of licorice root, has shown antioxidative properties. This study was to investigate the effects and mechanisms of licochalcone B in ethanol-induced hepatic injury in an in vitro study. Materials and Methods: An in vitro model of Ethanol-induced cytotoxicity in BRL cel...

Redox sensitive transcription factors nuclear factor kappaB (NF-kappaB) and activator protein-1 are involved in the pathogenesis of alcohol-induced disorders. Because of its antioxidative properties, vitamin E may help prevent oxidative stress-induced disorders. The aim of the present study was to delineate the molecular mechanisms associated with alcohol-induced oxidative stress and to see whe...

background: alcohol is a potent teratogen and alcohol use in pregnancy and the periconception period can cause many complications in mother, fetus and neonate.  discussion: alcohol in the mother's blood passes through the placenta to the baby through the umbilical cord. drinking alcohol during pregnancy can cause miscarriage, stillbirth, and a range of lifelong disorders. alcohol-related birth ...