نتایج جستجو برای: aldrich
تعداد نتایج: 3555 فیلتر نتایج به سال:
BACKGROUND T-cell activation relies on the assembly of the immunological synapse, a structure tightly regulated by the actin cytoskeleton. The precise role of the Wiskott-Aldrich syndrome protein, an actin cytoskeleton regulator, in linking immunological synapse structure to downstream signaling remains to be clarified. DESIGN AND METHODS To address this point, CD4(+) T cells from patients wi...
Wiskott-Aldrich syndrome is a rare X-linked recessive disease resulting from variations in the WAS gene. Wiskott-Aldrich syndrome is sometimes difficult to differentiate from immune thrombocytopenic purpura. A 2-month-old boy was admitted to our hospital for purpura and thrombocytopenia. His mean platelet volume was reported to be normal. Treatment with intravenous immunoglobulins failed to imp...
Abstract Estimating the ideological positions of political actors is an important step toward answering a number substantive questions in science. Survey scales provide useful data for such estimation, but also present challenge, as respondents tend to interpret differently. The Aldrich–McKelvey model addresses this existing implementations still have notable shortcomings. Focusing on Bayesian ...
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