نتایج جستجو برای: allotransplantation
تعداد نتایج: 888 فیلتر نتایج به سال:
BACKGROUND This study aimed to establish the expression profile of circulating microRNAs (miRNAs) during nerve allotransplantation in the presence and absence of FK506 immunosuppression. METHODS A 1 cm BALB/c donor sciatic nerve graft was transplanted into the sciatic nerve gaps created in recipient C57BL/6 mice with or without daily FK506 immunosuppression [1 mg/(kg·d)]. At 3, 7, and 14 d af...
several factors including cancer, malformations and traumas may cause large facial mutilation. these functional and aesthetic deformities negatively affect the psychological perspectives and quality of life of the mutilated patient. conventional treatments are prone to fail aesthetically and functionally. the recent introduction of the composite tissue allotransplantation (cta), which uses tran...
Rats are the most frequently used animals in composite tissue allotransplantation (CTA) studies and most craniofacial composite tissue transplantation models are described in rats. During the last 10 years, a total of 8 different craniofacial composite tissue allotransplantation (CCTA) models have designed and developed in rats. These models include full face/scalp transplants, hemiface transpl...
Permanent hypoparathyroidism is a serious clinical situation. Allotransplantation of the parathyroid cells is relatively new approach to treatment. Non-cultivated allotransplantation in rabbits is not tried before. In this research parathyroidectomy was performed in six female New Zealand white rabbits. After division of surgically removed tissues into two, cryopreservation after cell isolation...
AIMS The aim of this work was to investigate different surgical options for the repair of the ocular surface, using various extensions of the procedure of limbal stem cell allotransplantation. METHODS/RESULTS Straightforward lamellar limbal transplantation was performed in one patient with contact lens induced limbal stem cell failure. A second patient with a neoplastic corneal lesion underwe...
In this article, we report on 904 patients undergoing transplantation for follicular lymphoma. A total of 176 (19%) received allogeneic, 131 (14%) received purged autologous, and 597 (67%) received unpurged autologous transplants. Five-year treatment-related mortality (TRM) rates were 30%, 14%, and 8% and 5-year recurrence rates were 21%, 43%, and 58% after allotransplantation, purged autotrans...
BACKGROUND Therapy-refractory persistent hypoparathyroidism after extensive neck surgery is a rare but severe complication. Parathyroid allotransplantation may represent a definitive treatment option. CASE PRESENTATION A 32-year old female was referred to our hospital with intractable persistent hypocalcemia after neck surgery for papillary thyroid cancer. Despite optimal medical treatment in...
background: cell therapy has emerged as a promising curative intervention for several diseases including diabetes and wolfram syndrome (ws). the current study aimed to assess the effectiveness of clinical application of fetal-liver derived stem cells for treatment of patients with ws. methods: six patients with ws aged 23-34 (mean: 29.50, sd: 4.76) were recruited for the current phase 3 single-...
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