Immunization of ewes with oil emulsion toxoid followed by an aluminium phosphate-adsorbed toxoid both containing 10 Lf per dose, resulted in a very high antitoxin level in their lambs. Two injections of aluminium phosphate-adsorbed toxoid also imparted a passive immunity to lambs which is considered to be adequate to protect them against tetanus for 4 weeks after birth.

Aluminium- or calcium-based phosphate-binding agents traditionally have been used to treat hyperphosphataemia in patients with end-stage renal disease. Although these agents effectively lower serum phosphorus levels, they are associated with serious side effects. Aluminium-based agents are associated with bone toxicity, renal osteodystrophy and encephalopathy, and calcium-based agents increase ...

Chronic aluminium exposure and toxicity related to aluminium absorption continue to be a problem for many patients with renal failure [1]. The two most prevalent sources of aluminium are water used to prepare dialysate and aluminium-containing phosphate binders. However, calcium-based binders, Sevelamer or others, have replaced aluminium phosphate binders and reverse osmosis has been used for w...

According to the Bricker-Slatopolsky theory, secretion of parathyroid hormone (PTH) is switched on in chronic renal failure by hypocalcaemia due to phosphate retention. In an attempt to reverse this process 20 patients in preterminal renal failure (plasma creatinine 569 +/- 195 mumol/l) were given aluminium hydroxide, 3.8 g daily. They were studied for four weeks and all measurements were made ...

BACKGROUND Control of dietary phosphate absorption in end-stage renal disease patients is essential to prevent the deleterious sequelae of phosphorus retention. Efficacy of currently available calcium- and aluminium-containing phosphate binders is constrained by the side-effects associated with the absorption of calcium and aluminium. The current study examined the efficacy of RenaGel, a calciu...

A controlled field trial to determine the efficacy of a single dose of an aluminium phosphate-adsorbed cholera vaccine was conducted in Calcutta during 1975-77. An aluminium phosphate-adsorbed tetanus toxoid was used as the placebo. Follow-up of the immunized volunteers for a period of two years showed that the adsorbed cholera vaccine provided 100% protection to children under five years of ag...

Introduction: Radiopacity is a necessary property for luting cements . The aim of this study was to investigate the radiopacity of some luting dental cements used in prosthetic dentistry. Methods: Five disclike samples of each material (6 x 1 mm) were prepared from panavia F2.0(Pa), Chioce2 (Ch.2), Glass ionomer GC (GI GC), zinc phosphate Hoffmann’s (ZP hof), zinc polycarboxylate Hoffm...