From the leaves of Chamaecyparis obtusa several biflavones were isolated and identified, namely: sciadopitysin, ginkgetin, isoginkgetin, podocarpusflavone B, 7,7"-O-dimethylamentoflavone, bilobetin, podocarpusflavone A, and 7-O-methylamentoflavone. The presence of amentoflavone and hinokiflavone was also confirmed. The composition of biflavones in other Chamaecyparis species--Ch. lawsoniana, Ch...

Amentoflavone (C30H18O10) is a well-known biflavonoid occurring in many natural plants. This polyphenolic compound has been discovered to have some important bioactivities, including anti-inflammation, anti-oxidation, anti-diabetes, and anti-senescence effects on many important reactions in the cardiovascular and central nervous system, etc. Over 120 plants have been found to contain this bioac...

Objective: This study aimed to isolate and identify the Bacillus subtilis antibacterial compound present in leaves of Garcinia latissima Miq.
 Methods: The extracts were obtained by maceration successively, active extract was fractionated column chromatography. isolation most fraction performed open chromatography preparative thin-layer assay against microdilution method. structure identif...

This study is the first phytochemical investigation of Selaginella sellowii and demonstrates the antileishmanial activity of the hydroethanolic extract from this plant (SSHE), as well as of the biflavonoids amentoflavone and robustaflavone, isolated from this species. The effects of these substances were evaluated on intracellular amastigotes of Leishmania (Leishmania) amazonensis, an aetiologi...

Novel natural compounds endowed with sound bioactivities are currently the utmost need as leads toward drug discovery. For the first time, here, we report the presence of Amentoflavone (biflavonoid) in the leaves of Cassia fistula L. Structural characterization was carried out using ultraviolet-visible spectrophotometer, Fourier transform infrared, nuclear magnetic resonance, and thin-layer chr...

The antiviral activity of total flavonoid extracts from Selaginella moellendorffii Hieron and its main constituents amentoflavone were investigated against coxsackie virus B3 (CVB3). When added during or after viral infection, the extracts and amentoflavone prevented the cytopathic effect (CPE) of CVB3, as demonstrated in a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) col...

Abstract Amentoflavone is one of the flavonoids that are known for their antiviral effects and many them predicted to have inhibitory against severe acute respiratory syndrome coronavirus (SARS-CoV) Middle East Coronavirus (MERS-CoV) enzymes 3-chymotrypsin-like protease (3CLpro) papain-like (PLpro). a biflavonoid found in herbal extracts St. John's wort ( Hypericum perforatum ), Gingko biloba ,...