gamma aminobutyric acid (gaba) is one of the inhibitory neurotransmitters that may have the ability torelieve the intensity of stress. heat stress remains a major threat for duck production in summer in most areas of china. the current study was conducted to investigate the effect of dietary gaba on performanceparameters and plasma metabolites of heat exposed ducks. two thousand cherry valley d...

The quantitative measurement of amino acids in different areas of the central nervous system has shown that a progressive increase takes place in levels of y-aminobutyric acid during development (2, 3), and that the concentration of this amino acid in adult brain is relatively constant under a variety of physiological stresses. y-Aminobutyric acid is synthesized by glutamic acid decarboxylase, ...

Sodium valproate and tomato extract have been studied in different experimental models of epilepsy individually. The aim of the present study was to evaluate the effect of lycopene on the antiepileptic effects of sodium valproate against pentylenetetrazol-induced kindling in mice. Swiss albino mice of either sex were randomly divided into 5 groups, with each group containing 8 mice. These group...

The value of lactulose treatment in hepatic encephalopathy is widely recognised but its mode of action remains controversial. Much evidence supports a role for gamma-aminobutyric acid in hepatic encephalopathy, and lactulose could alter its bacterial production in the gut. Using the rat synaptic membrane assay and gas chromatography mass spectrometry, the production of gamma-aminobutyric acid b...

The objective of this study was to investigate the role of β-aminobutyric acid(BABA) (0, 300µM) in reduction of oxidative damages in leaves and roots of Brassica napus L. under drought stress (0, -0.2, -0.4 MPa). β-aminobutyric acid was investigated as an internal regulator hormone and its role in defense  mechanisms against biotic and abioticstresses. In this study, BABA pretreatment prevented...

BACKGROUND Gamma-aminobutyric acid is a major inhibitory neurotransmitter in mammalian brains, and has several well-known physiological functions. Lactic acid bacteria possess special physiological activities and are generally regarded as safe. Therefore, using lactic acid bacteria as cell factories for gamma-aminobutyric acid production is a fascinating project and opens up a vast range of pro...

The action of pentobarbital on primary afferents of the isolated frog spinal cord was analyzed with sucrose gap and intracellular recordings techniques. Pentobarbital in concentrations generally considered to be in the anesthetic range greatly prolonged presynaptic inhibition and also depolarized primary afferents. The depolarization was accompanied by an increase in excitability and resulted f...

glutamate decarboxylase enzyme produces γ-aminobutyric acid (gaba) in a non-reversible decarboxylation reaction of glutamate. gaba is a major inhibitory neurotransmitter of the brain and it is also present at high concentration in other organs such as pancreatic islets. gaba has effects on blood pressure, diabetes, inflammation, sleeplessness and depression. some bacteria such as lactobacillus ...

An enzyme which catalyses dehydrogenation of y-aminobutyraldehyde (ABAL) to y-aminobutyric acid (GABA) was purified to homogeneity from rat brain tissues by using DEAE-cellulose and affinity chromatography on 5'AMP-Sepharose, phosphocellulose and Blue Agarose, followed by gel filtration. Such an enzyme was first purified from mammalian brain tissues, and was identified as an isoenzyme of aldehy...

The seasonal and daily dynamics of the content nitrogen-containing compounds in leaves Hylotelephium triphyllum plants was studied. maximum total nitrogen, soluble protein free amino acids observed regrowth phase, followed by their reduction towards end growing season. characterized a high low morning hours. In H. , 23 2 amides were found. determined glutamine glutamic acid. 4 non-proteinogenic...