Quaternary ammonium compounds are an important class of molecules with wide variety of applications, mainly in the antimicrobial field. Quaternary ammonium compounds have the ability to bind with the anionic moiety of phospholipids of the bacterial membrane, disrupting the cell membrane of the microorganisms. However, classical quaternary ammonium salts can have adverse effects on the environme...

Tests to determine the potential use of a quaternary ammonium resin-triiodide complex as a sterilizing agent showed that it was an ineffective sporicide and that bactericidal activity was impaired by complex milieu.

MCCULLOCH, E. C. 1947 The real and apparent bactericidal efficiencies of quaternary ammonium compounds. J. Bacteriol., 53: 370. MCCULLOCH, E. C., HAUGE, S., AND MIGAKI, H. 1948 The role of disinfectants in veterinary medicine. II. A critical evaluation of the quaternary ammonium compounds. J. Am. Vet. Med. Assoc., 112: 283-290. STUART, L. S. 1947 N.A.I.D.M.-U.S.D.A. report on quaternary ammoniu...

The study of good nonregular fractional factorial designs has received significant attention over the last two decades. Recent research indicates that designs constructed from quaternary codes (QC) are very promising in this regard. The present paper shows how a trigonometric approach can facilitate a systematic understanding of such QC designs and lead to new theoretical results covering hithe...

Virucidal activity of immobilized quaternary ammonium compounds (IQACs) coated onto glass and plastic surfaces was tested against enveloped influenza A (H1N1) virus and nonenveloped poliovirus Sabin1. The IQACs tested were virucidal against the influenza virus within 2 min, but no virucidal effect against poliovirus was found in 6 h.

Quaternary ammonium compounds (QACs) have raised considerable attention due to their wide commercial applications and recent discovery of unknown persistent analogues in aqueous environment. In this work, the occurrence and distribution of alkyltrimethylammonium (ATMAC), benzylakyldimethylethylammonium (BAC) and dialkyldimethylammonium (DADMAC) homologues were investigated in fifty-two municipa...

DESCRIPTION The active ingredient in ATROVENT (ipratropium bromide) Inhalation Aerosol is ipratropium bromide. It is an anticholinergic bronchodilator chemically described as 8azoniabicyclo[3.2.1]-octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1methylethyl)-, bromide, monohydrate (endo,syn)-,(±): a synthetic quaternary ammonium compound chemically related to atropine. The structural fo...

The evaluation of germicides has been the subject of considerable controversy. At the present time, the phenol coefficient method is the official procedure of the Association of Official Agricultural Chemists (1950) for the evaluation of water-soluble germicides. However, Klarmann and Wright (1946), McCulloch (1947), DuBois (1947), McCulloch, Hauge, and Migaki (1948), and Stuart, Boguskey and F...