The soluble form of the inhibitory immune receptor leukocyte-Associated Ig-like Receptor-1 (sLAIR-1) is present in plasma, urine and synovial fluid and correlates to inflammation. We and others previously showed inflammatory protein expression in normal amniotic fluid at term. We hypothesized that sLAIR-1 is present in amniotic fluid during term parturition and is related to fetal lung function...

Fetal swallowing of amniotic fluid, which contains numerous cytokines and growth factors, plays a key role in gut mucosal development. Preterm birth interrupts this exposure to amniotic fluid-borne growth factors, possibly contributing to the increased risk of necrotizing enterocolitis (NEC) in premature infants. We hypothesized that supplementation of formula feeds with amniotic fluid can prov...

the purpose of this experimental study was to evaluate the effect of chicken amniotic fluid (af) on a cross section of rat sciatic nerves. thirty adult male sprague-dawley rats weighing 275 to 300 g, were randomized into three groups treated with (1) amniotic fluid or af (n=10), (2) normal saline or ns (n=10), and (3) sham surgery (n=10). the af was aspirated from the amniotic cavity of incubat...

OBJECTIVE We explored the possibility that perturbations in amniotic fluid glucose, insulin, and insulin-like growth factor-binding protein 1(IGFBP1) and/or metabolic acids exist before routine screening for GDM. RESEARCH DESIGN AND METHODS We selected consenting mother-infant pairs (n = 408) who met our inclusion criteria (singleton pregnancy, no genetic abnormalities, and no preexisting dia...

Little is known about the origin of albumin in amniotic fluid. A fetal origin is questionable, because of the low concentration of protein in fetal urine and lung fluid. A maternal origin of proteins in amniotic fluid was already proposed in the 1970s. This review focuses on the possible sources of albumin in amniotic fluid and on the pathways for albumin to enter and leave the amniotic fluid i...

although amniotic fluid embolism is a rare event, but it is a tragic event. this kind of embolism occurs in 1 per 20,000 to 30,000 births with 86% maternal mortality rate in the united states. amniotic fluid embolism is in charge of near 10-15% of all maternal deaths. this article reflects the experiences of a nurse midwife encountered with a maternal and neonatal death due to an amniotic fluid...

OBJECTIVE To test the hypothesis that unconjugated bilirubin is equally distributed over the albumin molecules present in fetal blood and amniotic fluid in Rhesus (Rh) immunization. METHODS Molar concentrations of unconjugated bilirubin and albumin were measured in fetal blood and amniotic fluid samples, obtained before the first intrauterine transfusion in 30 nonhydropic, anti-D-alloimmunize...

INTRODUCTION Amniotic fluid is an important factor in the prediction of fetal survival. The aim of this research was to evaluate the effects of intravenous hydration of mothers on amniotic fluid volume and in turn on pregnancy outcomes. METHODS The current single blind controlled clinical trial was conducted on 20 pregnant mothers with amniotic fluid index of lower or equal to 5 cm and gestat...

We amplified bacterial 16S rRNA encoding DNA (rDNA) with the polymerase chain reaction (PCR) to detect amniotic fluid infection in 69 women in premature labor whose membranes were intact. Bacterial rDNA was detected by PCR in samples from 15 (94%) of 16 patients with positive amniotic fluid cultures. Bacteria were detected by PCR in samples from 5 (36%) of 14 patients with negative cultures and...

Eight fatty acids (C12-C18) were previously identified in human amniotic fluid, colostrum, and milk in similar proportions but different amounts. Amniotic fluid is well known to be the natural environment for development in mammals. Interestingly, amniotic fluid and an artificial mixture of fatty acids contained in amniotic fluid produce similar anxiolytic-like actions in Wistar rats. We explor...