The goal of the present study was to identify the projection from the subdivisions of the amygdaloid nuclear complex to specified subregions of the dorsal raphe (DR) nucleus and to attempt to compare the density of amygdaloid input to the DR with that of inputs from other limbic structures. Use of a retrograde tracer, gold-conjugated and inactivated wheatgerm agglutinin-horseradish peroxidase (...

Structures and connections in the medial temporal lobe of humans and nonhuman primates have long been recognized as important for normal memory and emotional behavior. The present study investigated memory and emotional behavior in normal monkeys and six groups of monkeys with lesions of the medial temporal lobe. Two groups had damage to the hippocampal formation (or adjacent perirhinal and par...

Few studies have investigated whether neuronal function in the amygdaloid complex is necessary for the occurrence of the cardiovascular response to natural (unconditioned) environmental threats. In the present investigation in conscious unrestrained Sprague-Dawley rats we inactivated neuronal function in the amygdaloid complex acutely (bilateral muscimol injections) or chronically (unilateral o...

CONTENTS Introduction ........................................................ Material and methods ............................................... Literature .......................................................... Description of material .............................................. Certain general characteristics of the brain of Tadarida ............ The nuclear groups ......................

Recent neurochemical results suggest the hypothesis that the nucleus basalis magnocellularis (nbm) cholinergic projection to the amygdala may play a role in memory. The present study investigated the effects of intra-amygdaloid injections of the cholinergic antagonist scopolamine on working and reference memory in the double Y-maze. Rats were pretrained until working and reference memory choice...

MORGANE, P. J. AND A. J. KOSMAN. A rhinence+halic feeding center in the cat. Am. J. Physiol. I g7( r ) : I 58-162. = 957*--Lesions of the rhinencephalon, primarily restricted to the pyriform lobe and amygdaloid complex, modifies the eating behavior of cats so that their food intakes and body weights are significantly increased. Neodecortication has no significant effect on either food intake or...

The mechanisms that regulate the development of the amygdaloid complex are as yet poorly understood. Here, we show that in the absence of the LIM-homeodomain (LIM-HD) gene Lhx2, a particular amygdaloid nucleus, the nucleus of the lateral olfactory tract (nLOT), is selectively disrupted. LIM family members are well suited for multiple roles in the development of complex structures because they p...

The distribution of several neuropeptides in the amygdaloid complex of the cat is described. Five of the neuropeptides studied (luteinizing hormone-releasing hormone, β-endorphin, dynorphin A (1-17), γ-melanocyte-stimulating hormone or galanin) did not show immunoreactive profiles, whereas neuropeptide Y and somatostatin displayed the widest distribution throughout the amygdaloid nuclei. The me...

The amygdala is a nuclear complex composed of 13 nuclei and cortical areas and their subdivisions. Tract-tracing studies performed over the past 20 years demonstrate that each nucleus is uniquely connected with other brain areas. Consistent with anatomic heterogeneity, the functions of the amygdala vary from attention to memory to formation of emotional responses to sensory stimuli. Here, we br...