نتایج جستجو برای: anastrazole

تعداد نتایج: 40  

Journal: :physiology and pharmacology 0
farshad moradpour department of physiologhy and pharmacology, pasteur institute of iran, pasteur avenue, 13164 tehran, iran nasser naghdi department of physiologhy and pharmacology, pasteur institute of iran, pasteur avenue, 13164 tehran, iran yaghob fathollahi department of physiologhy, tarbiat modares university, p.o. box 14115-116, tehran, iran

introduction: sexhormones are one of most important factors in difference of learning and memory between tow sexes (male & female). high concentration of estrogen and androgen receptors and mechanism of testosterone and estrogen production in learning and memory center, especially in hippocampus show the role of this receptors, sexhormons and p450 enzymes in spatial memory. consequently, in thi...

Journal: :The Surgical clinics of North America 2013
Richard J Bleicher

Management of ductal carcinoma in situ (DCIS) has evolved from radical surgery to the option of a more minimally invasive approach. Data show that breast conservation surgery performed with administration of radiotherapy, like mastectomy, is feasible and safe. Because efforts to find a safe group for elimination of radiotherapy have resulted in data that conflict, radiotherapy still remains sta...

2013
Shaun Treweek Ruth Dryden Colin McCowan Alison Harrow Alastair Thompson

Results 33 breast cancer specialists ranked 39 trials in order of importance with the 12 most selected included in this study. Of 4811 women in the Tayside dataset, the number meeting eligibility criteria for the 12 trials ranged from 822 (17%) to 3419 (71%). Reasons for exclusion included age and comorbidity. Many women received a treatment evaluated in a trial but would themselves not have be...

2013
Amparo C Villablanca Sarada Tetali Robin Altman Kenneth F Ng John C Rutledge

Vascular endothelium expresses both the estrogen receptors (ERs) α and β, and ERα mediates development of early atherosclerosis in male mice. This process is thought to be testosterone-dependent. We hypothesized that male murine aortic endothelium produces robust levels of estradiol by aromatase conversion of testosterone, and that regulation of this process is mediated by the presence of ERs, ...

Journal: :Circulation 2007
Joanne E Nettleship T Hugh Jones Kevin S Channer Richard D Jones

BACKGROUND Research supports a beneficial effect of physiological testosterone on cardiovascular disease. The mechanisms by which testosterone produces these effects have yet to be elucidated. The testicular feminized (Tfm) mouse exhibits a nonfunctional androgen receptor and low circulating testosterone concentrations. We used the Tfm mouse to determine whether testosterone modulates atheroma ...

Journal: :International journal of radiation oncology, biology, physics 2007
Richard Pötter Michael Gnant Werner Kwasny Christoph Tausch Leonore Handl-Zeller Brigitte Pakisch Susanne Taucher Josef Hammer Gero Luschin-Ebengreuth Marianne Schmid Felix Sedlmayer Michael Stierer Georg Reiner Karin Kapp Friedrich Hofbauer Andrea Rottenfusser Sabine Pöstlberger Karin Haider Wolfgang Draxler Raimund Jakesz

PURPOSE In women with favorable early breast cancer treated by lumpectomy plus tamoxifen or anastrazole, it remains unclear whether whole breast radiotherapy is beneficial. METHODS AND MATERIAL Between January 1996 and June 2004, the Austrian Breast and Colorectal Cancer Study Group (ABCSG) randomly assigned 869 women to receive breast radiotherapy +/- boost (n = 414) or not (n = 417) after b...

Journal: :Fertility and sterility 2011
Amy Baigent Hany Lashen

OBJECTIVE To report the management of a rare case of ovarian hyperstimulation syndrome (OHSS) induced by tamoxifen therapy for breast cancer in a 50-year-old woman. DESIGN Case report. SETTING Gynecology outpatient department of a university hospital. PATIENT(S) A 50-year-old premenopausal patient with a history of breast cancer was prescribed adjuvant treatment with tamoxifen. INTERVEN...

2014
Nazife Sule Yasar Bilge Cengiz Korkmaz

Aromatase inhibitors (AIs) are the indispensible part of hormone-responsive breast cancer treatment. A potential relation between autoimmunity and AIs has been described before. Herein, we report a case of Sjogren's syndrome (SjS) and polyneuropathy which developed during treatment with anastrozole. A 70 years old female patient having a history of breast cancer was referred to our clinic with ...

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