a Department of Mechanical and Industrial Engineering, University of Illinois at Chicago, 842W. Taylor St., Chicago, IL 60607-7022, USA b School of Mechanical Engineering, Korea University, Seoul, 136-713, Korea c School of Civil, Environmental & Architectural Engineering, Korea University, Seoul 136-713, Korea d Department of Environmental Science & Ecological Engineering, Korea University, Se...

INTRODUCTION Early diagnosis of and subsequent monitoring of therapy for rheumatoid arthritis (RA) could benefit from detection of (sub)clinical synovitis. Imaging of (sub)clinical arthritis by targeting the translocator protein (TSPO) on activated macrophages is feasible using (R)-[¹¹C] PK11195-based positron emission tomography (PET), but clinical applications are limited by background uptake...

UNLABELLED The induction of neuroinflammatory processes, characterized by upregulation of the peripheral benzodiazepine receptor (PBR) expressed by microglial cells, is well correlated with neurodegenerative diseases and with acute neuronal loss. The continually increasing incidence of neurodegenerative diseases in developed countries has become a major health problem, for which the development...

Current tools for monitoring response to tuberculosis treatments have several limitations. Noninvasive biomarkers could accelerate tuberculosis drug development and clinical studies, but to date little progress has been made in developing new imaging technologies for this application. In this study, we developed pulmonary single-photon emission computed tomography (SPECT) using radioiodinated D...

A major productivity hurdle for parallel programming is the presence of data races. Data races can lead to all kinds of harmful program behaviors, including determinism violations and corrupted memory. However, runtime overheads of current dynamic data race detectors are still prohibitively large (often incurring slowdowns of 10× or more) for use in mainstream software development. In this pape...

Pleiotrophin (PTN) was found to regulate tyrosine phosphorylation of beta-adducin through the PTN/receptor protein tyrosine phosphatase (RPTP)beta/zeta signaling pathway. We now demonstrate that PTN stimulates the phosphorylation of serines 713 and 726 in the myristoylated alanine-rich protein kinase (PK) C substrate domain of beta-adducin through activation of either PKC alpha or beta. We also...

16 17 18 19 Contact Information: 20 Edgar T. Walters, Ph.D. 21 Department of Integrative Biology and Pharmacology 22 University of Texas Medical School at Houston 23 Houston, TX 77030 24 Office: 713 – 500 – 6314 25 Fax: 713 – 500 – 7444 26 [email protected] 27 28 29 Abstract: 250 words 30 Pages: 36 31 Figures: 6 32 Tables: 0 33 34

1.1. Field extensions. Suppose K is a field containing a subfield F . An element α ∈ K is called algebraic over F if there exists a non-zero polynomial f ∈ F [x] such that f(α) = 0. If α is algebraic over F , the set Iα(F ) := {f ∈ F [x] | f(α) = 0} is a non-zero ideal of F [x] (this is easy, but do check it). Since F [x] is a PID (it is in fact a Euclidean ring with respect to the degree funct...