Medullary thyroid cancer accounts for 5-10% of thyroid carcinomas. RET proto-oncogene mutations occur in all of the hereditary MTCs and about 66% of the sporadic MTCs. So, the detection of the RET mutations is necessary for rapid and proper diagnosis and treatment. This systematic review seeks to find a comprehensive list of RET gene mutations in the diagnosis of medullary thyroid cancer. The ...

the present article investigates the administrative structure of the pottery mound from an administrative management point of view. data obtained from excavation of the pottery mound has generated an extensive archeological databank relating to the beginning of the historical era with a focus on the emergence of management and administrative systems in the central iranian plateau. in the proto-...

meduiiary thyroid carcinoma (mtc) occurs both sporadically and in the autosomal dominantly inherited multiple endocrine neoplasia (men) type 2 syndromes. the distinction between true sporadic mtc and a new mutation familial case is important for future clinical management of both the patient and family. the susceptibility gene for hereditary mtc is the ret proto-oncogene. dna analysis for germl...

Crystallization of calcium carbonate, typically, progresses sequentially via metastabIc phases. Amorphous CaC03 (ACC) generally forms initially, both in vitro and in vivo, and is the precursor of the predominant anhydrous polymorphs (calcite, aragonite, and vaterite). [I-I3] A new picture of the crystallization of calcium carbonate is emerging, which involves transformations of clusters to ACC ...

background and aims. various morphologies are seen in different salivary gland tumorsor within an individual tumor, and the lesions show divers biological behaviors. experimental results support the hypothesis that increased crkii proto-oncogene is associated with cytokine-induced tumor initiation and progression by altering cell motility signaling pathway. the aim of this study was to assess t...

ABSTRACT Proto ols or part of proto ols are frequently reused through proje ts if they are suÆ iently generi . For instan e, the Contra t Net proto ol an be used verbatim or in other proto ols su h as the supply hain management. This reusability might be diÆ ult to do due to the la k of reusability in urrent intera tion proto ol formalisms. In this paper, we present a new approa h based on a mo...

Linguistics and archaeology have been, and continue to be, entwined in the discourse on the early human history of the Pacific. It is commonly assumed, explicitly or otherwise, that the bearers of the Lapita culture were speakers of Proto-Oceanic, the ancestor of the Austronesian languages of most of the Pacific. In this discursive piece, the chronological data for the location and timing of th...