The effect of natural androgens on serum lipids and atherosclerosis is controversial. We therefore studied this important issue prospectively in an animal model of atherosclerosis. Eighty male rabbits were randomized to bilateral castration, and 20 animals were sham operated. The castrated rabbits were randomized to 500 mg oral dehydroepiandrosterone (DHEA) daily, 80 mg oral testosterone undeca...

anti-androgens are an assorted group of drugs and compounds that reduce the levels or activity of androgen hormones within the human body. disease states in which this is relevant include polycystic ovarian syndrome, hirsutism, acne, benign prostatic hyperplasia, and endocrine related cancers such as carcinoma of the prostate. we provide an overview and discussion of the use of anti-androgen me...

Energy metabolism in humans is tuned to distinct sex-specific functions that potentially reflect the unique requirements in females for gestation and lactation, whereas male metabolism may represent a default state. These differences are the consequence of the action of sex chromosomes and sex-specific hormones, including estrogens and progesterone in females and androgens in males. In humans, ...

Brown adipose tissue (BAT) burns substantial amounts of mainly lipids to produce heat. Some studies indicate that BAT activity and core body temperature are lower in males than females. Here we investigated the role testosterone its receptor (the androgen receptor; AR) metabolic male mice. Castration, which renders mice deficient, slightly promoted expression thermogenic markers BAT, decreased ...

introduction: nymphea lotus linn (n. lotus) flowers are used empirically for the treatment of male sexual disorders in cameroon west region. this study was aimed to evaluate the effects of the n. lotus on some parameters of male fertility in adult albino male rats. methods: twenty four male rats were divided in 4 groups (n=6 each) and subjected to the following treatment: distilled water as veh...

Aim: Androgens are hormones that essential for the differentiation and development of male genital organs, preserving their structural features maintaining functions. These exert effects on target tissues mainly through androgen receptors (AR). The aim this study was to determine AR immunoexpression pattern in mice. Materials Methods: A total 6 BALB/c mice were anesthetized with ether, tissues,...