BACKGROUND/AIMS This study aimed to verify the reliability of the alcoholic liver disease (ALD)/nonalcoholic fatty liver disease (NAFLD) index (ANI) for distinguishing ALD in patients with hepatic steatosis from NAFLD, and to investigate whether ANI combined with γ-glutamyl transferase (GGT) would enhance the accuracy of diagnosis in China. METHODS A hundred thirty-nine cases of fatty liver d...

clature Subcommittee (http://www.allergen.org/). Two of these, Ani s 2 (paramyosin) and Ani s 3 (tropomyosin), are considered pan-allergens with low specificity [13] , which makes them unsuitable as specific targets for immunoassays. The remaining group includes 3 major allergens (Ani s 1, Ani s 7, and Ani s 12) and 7 minor allergens (Ani s 4, Ani s 5, Ani s 6, Ani s 8, Ani s 9, Ani s 10, and A...

OBJECTIVE We investigated the clinical anatomy of the levator ani nerve and its topographical relationship with the pudendal nerve. METHODS Ten female pelves were dissected and a pudendal nerve blockade was simulated. The course of the levator ani nerve and pudendal nerve was described quantitatively. The anatomical data were verified using (immuno-)histochemically stained sections of human f...

INTRODUCTION Pain is highly prevalent in critically ill trauma patients, especially those with a traumatic brain injury (TBI). Behavioral pain tools such as the behavioral pain scale (BPS) and critical-care pain observation tool are recommended for sedated noncommunicative patients. Analysis of heart rate variability (HRV) is a noninvasive method to evaluate autonomic nervous system activity. T...

Movement responses to noxious stimuli during general anesthesia are regarded as a sign of nociception. We compared the qNOX Index and Analgesia Nociception Index (ANI) as predictors of movement during propofol and remifentanil anaesthesia. Both indices are compared using the calculated propofol/remifentanil effect site concentrations (Ce) and the response to noxious stimuli recorded in 20 patie...

On-site mortality in crush syndrome remains high due to lack of effective drugs based on definite diagnosis. Anisodamine (Ani) is widely used in China for treatment of shock, and activation of α7 nicotinic acetylcholine receptor (α7nAChR) mediates such antishock effect. The present work was designed to test whether activation of α7nAChR with Ani decreased mortality in crush syndrome shortly aft...

Finding evidence of anisakidosis requires invasive methods. We have developed a serological assay based on the detection of an immunoglobulin E (IgE) specifically directed against Ani s 1 protein, a major parasite allergen of Anisakis simplex, which has shown a high level of accuracy in the diagnosis of anisakidosis. We used this tool to determine the prevalence of anti-Ani s 1 IgE in dyspeptic...

Pruritus ani is an unpleasant cutaneous sensation that induces the desire to scratch the skin around the anal orifice. It may start insidiously and appears in 1% to 5% of the population. It is classified as primary (idiopathic) pruritus ani when no cause can be found. However, as 25% to 75% of cases have co-existing pathology, a detailed history and examination are necessary. The goal of treatm...

We employed RU 38486, a potent and selective antiglucocorticoid, to study a possible role for endogenous glucocorticoids in atrophy of the levator ani muscle secondary to castration of male rats. RU 38486 was shown to block [3H]triamcinolone acetonide binding to cytosol from levator ani muscle. Daily oral administration of RU 38486 to castrated rats partially prevented atrophy of the levator an...