BACKGROUND studies in humans and animals have shown that following tooth removal (loss), the alveolar ridge becomes markedly reduced. Attempts made to counteract such ridge diminution by installing implants in the fresh extraction sockets were not successful, while socket grafting with anorganic bovine bone mineral prevented ridge contraction. AIM to examine whether grafting of the alveolar s...

This study investigated a minimally invasive surgical procedure for alveolar ridge augmentation that combined recombinant human platelet-derived growth factor BB (rhPDGF-BB) and three different matrices. The minimally invasive tunneling ridge augmentation procedure was applied to 12 patients randomized into three groups: rhPDGF-BB (0.3 mg/mL) was combined with freeze-dried bone allograft (FDBA;...

Introduction P-15 a fifteen residue synthetic peptide (GTPGPQGIAGQRGVV), is a structural analogue of the cell binding domain of Type 1 collagen [1]. P-15 adsorbed on anorganic bovine mineral (ABM-P15) scaffolds has been shown to enhance bone marrow stromal cell growth [2]. This study aimed to investigate the osteogenic potential of human dental pulp stromal cells (HDPSCs) in monolayer culture c...

The aim of this study was to investigate the possible use and ultimate fate of anorganic xenogenic bone for the restoration of defects in the maxillae and mandibles of adult rabbits. Furthermore, anorganic xenogenic bone was compared with implanted autogenous bone particles with regard to the response of the surrounding connective tissue and possible resorption of these implants by multinucleat...

The present article describes a titanium mesh procedure used for bone augmentation in the treatment of severe maxillary atrophy. A mix of iliac cancellous bone and anorganic bovine bone in a 1:1 ratio is proposed for achieving the best bone quality at the time of implant placement, which is performed 5 to 6 months after the augmentation surgery. This procedure provides for 3-stage surgery using...

Dear Editor, We are writing this letter with regard to an article recently published in Clinical Implant Dentistry and Related Research by Yeoungsug Kim and colleagues, entitled “Risk of Prion Disease Transmission through Bovine-Derived Bone Substitutes: A Systematic Review” (2013; 15:645–653). The aim of the article was “to assess the risk of BSE transmission through anorganic bovine bone subs...