نتایج جستجو برای: anp model

تعداد نتایج: 2107867  

Journal: :American journal of physiology. Lung cellular and molecular physiology 2010
Anna A Birukova Junjie Xing Panfeng Fu Bakhtiyor Yakubov Oleksii Dubrovskyi Jennifer A Fortune Alexander M Klibanov Konstantin G Birukov

Increased levels of atrial natriuretic peptide (ANP) in the models of sepsis, pulmonary edema, and acute respiratory distress syndrome (ARDS) suggest its potential role in the modulation of acute lung injury. We have recently described ANP-protective effects against thrombin-induced barrier dysfunction in pulmonary endothelial cells (EC). The current study examined involvement of the Rac effect...

2010
Paul M. McKie Alessandro Cataliotti Guido Boerrigter Horng H. Chen S. Jeson Sangaralingham Fernando L. Martin Tomoko Ichiki John C. Burnett

M-atrial natriuretic peptide (ANP; M-ANP) is a novel next generation 40 amino acid peptide based on ANP, which is highly resistant to enzymatic degradation and has greater and more sustained beneficial actions compared with ANP. The current study was designed to advance our understanding of the therapeutic potential of M-ANP in a canine model of acute angiotensin II–induced hypertension with el...

Journal: :Hypertension 2010
Paul M McKie Alessandro Cataliotti Guido Boerrigter Horng H Chen S Jeson Sangaralingham Fernando L Martin Tomoko Ichiki John C Burnett

M-atrial natriuretic peptide (ANP; M-ANP) is a novel next generation 40 amino acid peptide based on ANP, which is highly resistant to enzymatic degradation and has greater and more sustained beneficial actions compared with ANP. The current study was designed to advance our understanding of the therapeutic potential of M-ANP in a canine model of acute angiotensin II-induced hypertension with el...

Journal: :Clinical science 1997
M T Rademaker C J Charles E A Espiner C M Frampton M G Nicholls A M Richards

1. Whereas many studies have detailed the effects of exogenous atrial natriuretic peptide (ANP) infusions in heart failure, and a limited number have examined the effects of brain natriuretic peptide (BNP), none have directly compared the bioactivity of similar doses of ANP and BNP under standard conditions of impaired cardiac function. We compared the hormonal, haemodynamic and renal effects o...

Journal: :Cardiovascular research 1999
R Willenbrock M Scheuermann G Thibault M Haass K Höhnel J Bohlender F C Luft R Dietz

OBJECTIVE In heart failure atrial natriuretic peptide (ANP) release in response to volume expansion is impaired while the renin-angiotensin system is activated. This study was designed to test the hypothesis that ANP release in heart failure is dependent on an activated angiotensin system. METHODS We studied the ANP and renin-angiotensin systems in a rat model of shunt-induced high-output hea...

Journal: :Journal of the American Society of Nephrology : JASN 2001
C Zoccali F Mallamaci F A Benedetto G Tripepi S Parlongo A Cataliotti S Cutrupi G Giacone I Bellanuova E Cottini L S Malatino

This study was designed to investigate the relationship among brain natriuretic peptide (BNP) and atrial natriuretic peptide (ANP) and left ventricular mass (LVM), ejection fraction, and LV geometry in a large cohort of dialysis patients without heart failure (n = 246) and to test the prediction power of these peptides for total and cardiovascular mortality. In separate multivariate models of L...

2017
Serdar Turkyilmaz Arif Burak Cekic Arif Usta Etem Alhan Birgül Vanizor Kural Cengiz Ercin Kutay Sağlam

Introduction: Ethyl pyruvate (EP), a natural flavoring and fragrance agent, has been shown to exert anti-inflammatory and antioxidant actions. We tested the potential beneficial effects of EP in a rat model of acute necrotizing pancreatitis (ANP), a serious condition with a significant inflammatory explosion and oxidative stress. Material and methods: Fifty-two adult male Sprague-Dawley rats we...

Journal: :Molecular vision 2005
Raquel Rollín Aránzazu Mediero Arturo Fernández-Cruz Raquel Fernández-Durango

PURPOSE Atrial natriuretic peptide (ANP) is a known vascular antipermeability and antiangiogenic factor, but its possible alteration during the early stages of diabetic retinopathy has not yet been explored. The present study sought to investigate the expression of ANP and its receptors using a model of streptozotocin (STZ) induced diabetes in the rat. METHODS Diabetes was induced in male Wis...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012
Hiroshi Kato Tomohiro Mizuno Masashi Mizuno Akiho Sawai Yasuhiro Suzuki Hiroshi Kinashi Fumiko Nagura Shoichi Maruyama Yukihiro Noda Kiyofumi Yamada Seiichi Matsuo Yasuhiko Ito

BACKGROUND Atrial natriuretic peptide (ANP) was recently reported to ameliorate fibrosis in the heart and experimental renal diseases and vascular thickening after balloon injury. Peritoneal fibrosis is an important complication of long-term peritoneal dialysis, and peritonitis is a factor in its onset. In the present study, we investigated the effects of ANP in a rat peritonitis-induced perito...

2015
Xiaoyu Chen Lifang Qiao

Web-based course is the important method in the landscape design teaching. In this paper, the ANP (Analytic Network Process) model has been adopted to evaluate the quality of the development of on-line courses, so as to provide the basis for preferred online courses. Conclude 10 evaluation indicators from 3 aspects of teaching, availability, and technology, and establish ANP model consisting of...

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