An immunohistochemical study was performed of changes in the expression of adhesion molecule CD44 in 32 adjacent non-tumour epithelia (ANTE) to lingual carcinomas and in the tumour tissue, using anti-CD44 monoclonal antibody DF1485. The aim was to evaluate the importance of these changes as an early event in lingual carcinogenesis. The ANTE was histologically normal in 22 cases (68.8%) and pres...

WHILST thrombo-embolism is a well recognised complication of the puerperium, ante-partum it is rare. No mention of its management is to be found in standard textbooks. Despite controversy concerning the value of anticoagulant treatment in arterial thrombotic disease, the efficacy of this therapy in venous thrombo-embolism is now well established. The apparent rarity of this condition in the ant...

how many patients are walking about suffering from the disease in a mild form in whom some of the major catastrophes never occur. 3. Its relationship to cancer is doubtful. Most writers say it is not a precursor, but W. T. Mayo found carcinoma in thirteen out of forty-two cases of diverticulitis. 4. It is hard to treat successfully. The treatment that is theoretically correct is often unsuitabl...

The percentage of S&P500 firms that offer ex-ante severance agreements to their CEOs grew from 20% in 1993 to more than 55% in 2007 despite controversial discussions on executive severance contracts in the media and academic studies. In addition, about 40% of firms offer their CEOs severance contracts with cash-only payouts. Our paper focuses on this recent spread of ex-ante CEO severance agree...

The paper studies bilateral contracting with endogenous property rights. Players engage in costly ex post adjustment of ex ante contract. After ex ante agreement on surplus sharing, players invest irreversibly production. Player costs of altering ex ante contract are transaction costs of three kinds: measurement, information and enforcement costs. Each player chooses an action which incurs tran...

Manufacturing is the locus of U.S. innovation, accounting for more than three quarters of U.S. corporate patents. The rise of import competition from China has represented a major competitive shock to the sector, which in theory could benefit or stifle innovation. In this paper we empirically examine how rising import competition from China has affected U.S. innovation. We confront two empirica...

are saved, which would not have been, had no ante-natal care been bestowed on the pregnant mother. Assuredly this is of the greatest importance, not only personally for the patient and her child but also socially for the country, which is being faced at present with a declining birth-rate, and thus everything possible should be done to aid the pregnant woman and her unborn child. This has not o...

In the past few years, there has been an increasing interest in developing project control systems. The primary purpose of such systems is to indicate whether the actual performance is consistent with the baseline and to produce a signal in the case of non-compliance. Recently, researchers have shown an increased interest in monitoring project’s performance indicators, by plotting them on the S...