substituted 1, 2, 4- triazoles have shown multiple biological activities such as anti-inflammatory, anti fungal, etc. 5-mercapto triazoles were prepared from the potassium dithiocarbazinates. these triazoles were used for preparation of different derivatives by two different schemes. in the first scheme the mannich bases were prepared from 5- marcapto-s triazole quinazolines. the 5-marcato-s-tr...

An efficient synthesis of some novel coumarin derivatives via 1, 4- Michael addition of indole to coumarin chalcones catalyzed by cellulose sulphonic acid (CSA) under solvent free conditions is described. The corresponding Michael addition products were obtained in good to excellent yield. The synthesized compounds were screened for their antibacterial activity against E. coli, S. aureus and an...

An efficient synthesis of some novel coumarin derivatives via 1, 4- Michael addition of indole to coumarin chalcones catalyzed by cellulose sulphonic acid (CSA) under solvent free conditions is described. The corresponding Michael addition products were obtained in good to excellent yield. The synthesized compounds were screened for their antibacterial activity against E. coli, S. aureus and an...

candida species are the most common cause of opportunistic fungal infection worldwide. due to increasing resistance of fungi against conventional drugs, as well as their side effects, alternative natural products have become a renewed interest. in the current study, the anti-candida activities of scrophularia striata extract were examined. in this experimental study, microdilution assay and wel...

non-steroidal anti-inflammatory drugs (nsaids) are the most common pharmacological group that has three primary therapeutic effects including anti-inflammatory, anti-pyrexia, and analgesia. in this study, seven of nsaids were tested against two species of skin pathogenic fungi (dermatophytes). percentage inhibition was determined for effective agents. diclofenac, aspirin and naproxen showed muc...